C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026932 Nacc2 10090 - 2:26055535-26123220 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028300 Nacc2-001 26055535-26122818 protein_coding
  ENSMUST00000114159 Nacc2-002 26055535-26092177 protein_coding
  ENSMUST00000126921 Nacc2-008 26061064-26062490 processed_transcript
  ENSMUST00000128674 Nacc2-007 26064492-26090375 processed_transcript
  ENSMUST00000133212 Nacc2-004 26089807-26123220 processed_transcript
  ENSMUST00000140993 Nacc2-006 26090086-26122783 protein_coding
  ENSMUST00000149408 Nacc2-005 26090328-26122788 processed_transcript
  ENSMUST00000152133 Nacc2-003 26064370-26091819 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028300ENSMUST00000114159ENSMUST00000140993ENSMUST00000152133
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028300 20.296±0.34 13.633±2.29 21.917±1.92 1.724±1.56 7.595±2.93 9.423±0.56 5.085±0.20 11.815±0.64 3.398±2.37 7.175±0.27 3.793±0.64 10.924±3.64 1.224±1.10 2.130±0.11
ENSMUST00000114159 N/A N/A N/A 2.129±0.25 1.737±0.00 N/A N/A N/A 0.280±0.08 N/A N/A N/A 0.364±0.00 N/A
ENSMUST00000140993 N/A N/A N/A N/A N/A 29.117±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000152133 N/A 15.992±2.21 N/A 1.666±0.00 12.687±2.77 12.198±1.93 N/A 10.203±0.17 1.274±0.00 6.766±0.37 N/A 13.632±2.43 0.648±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001F0 CIL_0001F0_0002 CGP 2:25998543-26123220

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IEA nuclear chromatin
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001076 IEA RNA polymerase II transcription factor binding transcription factor activity
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0004407 IEA histone deacetylase activity
GO:0005634 ISS nucleus
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0008285 IEA negative regulation of cell proliferation
GO:0010608 IEA posttranscriptional regulation of gene expression
GO:0016575 IEA histone deacetylation
GO:0016581 IEA NuRD complex
GO:0034629 IEA cellular protein complex localization
GO:0042803 IEA protein homodimerization activity
GO:0042826 IEA histone deacetylase binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:1900477 IEA negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter
GO:1902231 IEA positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077425 NACC2 NACC family member 2, BEN and BTB (POZ) domain containing protein_coding Danio_rerio
ENSG00000148411 NACC2 NACC family member 2, BEN and BTB (POZ) domain containing protein_coding Homo_sapiens

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