C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 17, subfamily A, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148795 CYP17A1 9606 - 10:102830531-102837533 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000369887 CYP17A1-001 102830531-102837533 protein_coding
  ENST00000469683 CYP17A1-004 102830948-102831703 retained_intron
  ENST00000489268 CYP17A1-002 102833475-102837414 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369887ENST00000469683ENST00000489268
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369887 0.041±0.00 0.131±0.00 11.725±0.00 0.111±0.00 0.067±0.00 0.142±0.00 0.104±0.06 3.468±3.18 4.083±4.05 N/A N/A 25.083±38.16 0.026±0.00 22.844±7.29
ENST00000469683 N/A N/A N/A N/A N/A N/A N/A 0.977±0.00 N/A N/A N/A N/A 0.183±0.00 N/A
ENST00000489268 0.114±0.00 0.147±0.00 N/A 0.174±0.02 0.081±0.00 0.140±0.00 0.087±0.00 N/A N/A 0.085±0.01 0.042±0.00 0.016±0.00 0.041±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MQ CIL_0008MQ_0001 VISTA 10:102469546-103070739
CIL_0001HV CIL_0001HV_0002 CGP 10:102743970-102837533
CIL_0001HW CIL_0001HW_0002 CGP 10:102830531-102864961

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004508 IDA steroid 17-alpha-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005739 IEA mitochondrion
GO:0005783 NAS endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006082 IEA organic acid metabolic process
GO:0006694 TAS steroid biosynthetic process
GO:0006702 TAS androgen biosynthetic process
GO:0006704 TAS glucocorticoid biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0007548 TAS sex differentiation
GO:0008202 IDA steroid metabolic process
GO:0008584 IEA male gonad development
GO:0009635 IEA response to herbicide
GO:0009636 IEA response to toxic substance
GO:0010033 IEA response to organic substance
GO:0010034 IEA response to acetate
GO:0010212 IEA response to ionizing radiation
GO:0014070 IEA response to organic cyclic compound
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0017085 IEA response to insecticide
GO:0018879 IEA biphenyl metabolic process
GO:0018894 IEA dibenzo-p-dioxin metabolic process
GO:0018958 IEA phenol-containing compound metabolic process
GO:0018963 IEA phthalate metabolic process
GO:0019825 TAS oxygen binding
GO:0020037 IDA:IEA heme binding
GO:0021766 IEA hippocampus development
GO:0030325 IEA adrenal gland development
GO:0030424 IEA axon
GO:0030728 IEA ovulation
GO:0031667 IEA response to nutrient levels
GO:0032526 IEA response to retinoic acid
GO:0033327 IEA Leydig cell differentiation
GO:0034097 IEA response to cytokine
GO:0034698 IEA response to gonadotropin
GO:0042446 IDA hormone biosynthetic process
GO:0042448 IDA progesterone metabolic process
GO:0042493 IEA response to drug
GO:0042995 IEA cell projection
GO:0043025 IEA neuronal cell body
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0047442 IEA 17-alpha-hydroxyprogesterone aldolase activity
GO:0048545 IEA response to steroid hormone
GO:0051591 IEA response to cAMP
GO:0051597 IEA response to methylmercury
GO:0055114 IEA oxidation-reduction process
GO:0060992 IEA response to fungicide
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071236 IEA cellular response to antibiotic
GO:0071371 IEA cellular response to gonadotropin stimulus
GO:0090031 IEA positive regulation of steroid hormone biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033566 cyp17a1 cytochrome P450, family 17, subfamily A, polypeptide 1 protein_coding Danio_rerio
ENSMUSG00000003555 Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 protein_coding Mus_musculus

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