C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 17, subfamily a, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003555 Cyp17a1 10090 - 19:46667165-46672974 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026012 Cyp17a1-001 46667165-46672974 protein_coding
  ENSMUST00000131142 Cyp17a1-003 46668087-46669513 retained_intron
  ENSMUST00000156577 Cyp17a1-002 46670726-46671291 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026012ENSMUST00000131142ENSMUST00000156577
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026012 0.071±0.00 0.157±0.03 0.004±0.00 0.023±0.01 0.162±0.08 0.044±0.00 0.093±0.03 0.109±0.05 32.844±27.07 0.032±0.01 0.024±0.00 135.884±53.51 38.580±32.51 82.207±24.42
ENSMUST00000131142 0.086±0.00 N/A 0.036±0.00 N/A 0.129±0.01 N/A 0.073±0.00 0.145±0.00 0.041±0.00 N/A N/A N/A N/A N/A
ENSMUST00000156577 0.257±0.12 N/A N/A 0.074±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MQ CIL_0008MQ_0002 VISTA 19:46318498-46919738
CIL_0001HV CIL_0001HV_0003 CGP 19:46599084-46672974
CIL_0001HW CIL_0001HW_0003 CGP 19:46667165-46703382

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004508 IMP steroid 17-alpha-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005739 IDA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0006082 IEA organic acid metabolic process
GO:0006694 IEA steroid biosynthetic process
GO:0006704 IDA glucocorticoid biosynthetic process
GO:0008202 ISS steroid metabolic process
GO:0008584 IEA male gonad development
GO:0009635 IEA response to herbicide
GO:0009636 IEA response to toxic substance
GO:0010033 IEA response to organic substance
GO:0010034 IEA response to acetate
GO:0010212 IEA response to ionizing radiation
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0017085 IEA response to insecticide
GO:0018879 IEA biphenyl metabolic process
GO:0018894 IEA dibenzo-p-dioxin metabolic process
GO:0018958 IEA phenol-containing compound metabolic process
GO:0018963 IEA phthalate metabolic process
GO:0020037 ISS heme binding
GO:0021766 IEA hippocampus development
GO:0030325 IEA adrenal gland development
GO:0030424 IDA axon
GO:0030728 IEA ovulation
GO:0031667 IEA response to nutrient levels
GO:0032526 IEA response to retinoic acid
GO:0033327 IEA Leydig cell differentiation
GO:0034097 IEA response to cytokine
GO:0034698 IEA response to gonadotropin
GO:0042446 ISS hormone biosynthetic process
GO:0042448 ISS progesterone metabolic process
GO:0042493 IEA response to drug
GO:0042995 IEA cell projection
GO:0043025 IDA neuronal cell body
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0047442 IEA 17-alpha-hydroxyprogesterone aldolase activity
GO:0048545 IEA response to steroid hormone
GO:0051591 IEA response to cAMP
GO:0051597 IEA response to methylmercury
GO:0055114 IEA oxidation-reduction process
GO:0060992 IEA response to fungicide
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071236 IEA cellular response to antibiotic
GO:0071371 IEA cellular response to gonadotropin stimulus
GO:0090031 IEA positive regulation of steroid hormone biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033566 cyp17a1 cytochrome P450, family 17, subfamily A, polypeptide 1 protein_coding Danio_rerio
ENSG00000148795 CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 protein_coding Homo_sapiens

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