C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adrenomedullin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148926 ADM 9606 + 11:10304680-10307397 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000278175 ADM-001 10304680-10307397 protein_coding
  ENST00000524948 ADM-005 10305077-10306260 protein_coding
  ENST00000525063 ADM-007 10305088-10306908 protein_coding
  ENST00000526492 ADM-006 10305088-10306530 protein_coding
  ENST00000528544 ADM-008 10305377-10306112 protein_coding
  ENST00000528655 ADM-002 10305084-10307355 protein_coding
  ENST00000530439 ADM-004 10305074-10307362 protein_coding
  ENST00000534464 ADM-003 10305073-10307395 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000278175ENST00000525063ENST00000526492ENST00000528655ENST00000530439ENST00000534464
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000278175 N/A N/A 0.487±0.00 0.560±0.00 N/A N/A 0.166±0.00 N/A N/A N/A N/A 3.528±3.01 18.588±0.00 N/A
ENST00000525063 310.676±0.00 8.493±0.00 N/A N/A 30.692±28.19 40.059±37.95 2.349±1.31 2.087±0.00 6.127±0.00 51.985±50.90 13.546±12.58 11.130±8.51 101.085±51.92 3.660±2.47
ENST00000526492 N/A N/A N/A N/A 2.414±0.00 N/A N/A 3.528±2.77 N/A N/A 1.317±0.00 N/A N/A N/A
ENST00000528655 N/A N/A 1.087±0.00 N/A 0.817±0.00 N/A N/A N/A N/A 1.262±0.00 N/A 0.934±0.00 33.199±0.00 N/A
ENST00000530439 N/A N/A 0.506±0.00 N/A 1.625±0.00 N/A N/A N/A 3.356±0.00 0.568±0.00 N/A 2.263±0.00 N/A 0.242±0.00
ENST00000534464 208.795±0.00 8.067±0.00 N/A 2.684±0.00 20.773±19.07 38.250±36.28 2.528±2.29 4.400±4.20 10.404±0.00 108.375±0.00 21.616±20.78 9.977±7.13 113.875±95.08 7.430±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004J7 CIL_0004J7_0001 CGP 11:9778667-10307397
CIL_0004JA CIL_0004JA_0001 CGP 11:10304680-10507579

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001570 IDA vasculogenesis
GO:0001666 IEA response to hypoxia
GO:0001843 IEA neural tube closure
GO:0002026 IEA regulation of the force of heart contraction
GO:0002031 IDA G-protein coupled receptor internalization
GO:0005102 TAS receptor binding
GO:0005179 IEA hormone activity
GO:0005515 IPI protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0006171 IDA cAMP biosynthetic process
GO:0006701 TAS progesterone biosynthetic process
GO:0007165 TAS signal transduction
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007267 TAS cell-cell signaling
GO:0007507 IEA heart development
GO:0007565 IEA female pregnancy
GO:0007568 IEA aging
GO:0008015 TAS blood circulation
GO:0008209 IEA androgen metabolic process
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 IEA negative regulation of cell proliferation
GO:0009409 IEA response to cold
GO:0009611 IEA response to wounding
GO:0010033 IEA response to organic substance
GO:0010460 IEA positive regulation of heart rate
GO:0019933 IEA cAMP-mediated signaling
GO:0030819 IDA positive regulation of cAMP biosynthetic process
GO:0031100 IEA organ regeneration
GO:0031102 IEA neuron projection regeneration
GO:0031623 IDA receptor internalization
GO:0031700 IEA adrenomedullin receptor binding
GO:0032496 IEA response to lipopolysaccharide
GO:0032868 IEA response to insulin
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0042594 IEA response to starvation
GO:0043065 IEA positive regulation of apoptotic process
GO:0043116 IEA negative regulation of vascular permeability
GO:0045766 IEA positive regulation of angiogenesis
GO:0045906 IDA negative regulation of vasoconstriction
GO:0045909 IEA positive regulation of vasodilation
GO:0046879 IEA hormone secretion
GO:0048589 IEA developmental growth
GO:0051384 IEA response to glucocorticoid
GO:0055074 IEA calcium ion homeostasis
GO:0060670 IEA branching involved in labyrinthine layer morphogenesis
GO:0060712 IEA spongiotrophoblast layer development
GO:0097084 IEA vascular smooth muscle cell development
GO:2001214 IEA positive regulation of vasculogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015263 adma adrenomedullin a protein_coding Danio_rerio
ENSMUSG00000030790 Adm adrenomedullin protein_coding Mus_musculus

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