C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adrenomedullin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030790 Adm 10090 + 7:110627661-110629820 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033054 Adm-201 110627669-110629819 protein_coding
  ENSMUST00000185766 Adm-002 110628028-110628551 retained_intron
  ENSMUST00000186620 Adm-001 110627661-110629820 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033054ENSMUST00000185766ENSMUST00000186620
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033054 11.936±1.25 11.688±4.93 7.856±2.02 0.711±0.30 6.572±1.69 6.852±0.75 7.740±1.27 6.399±0.57 1.360±0.74 4.679±0.44 1.209±0.18 8.608±2.61 20.332±12.60 0.392±0.19
ENSMUST00000185766 N/A N/A N/A N/A N/A N/A N/A N/A 0.553±0.11 N/A N/A N/A N/A N/A
ENSMUST00000186620 N/A 3.430±0.00 1.804±0.00 N/A N/A N/A N/A N/A 0.934±0.24 N/A N/A 1.539±0.00 3.714±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004J7 CIL_0004J7_0002 CGP 7:110308013-110629820
CIL_0004JA CIL_0004JA_0002 CGP 7:110627661-110812405

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001570 IEA vasculogenesis
GO:0001666 IEA response to hypoxia
GO:0001843 IMP neural tube closure
GO:0002026 IEA regulation of the force of heart contraction
GO:0002031 IEA G-protein coupled receptor internalization
GO:0005179 IEA hormone activity
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0006171 IEA cAMP biosynthetic process
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007507 IMP heart development
GO:0007565 IEA female pregnancy
GO:0007568 IEA aging
GO:0008209 IEA androgen metabolic process
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 IEA negative regulation of cell proliferation
GO:0009409 IEA response to cold
GO:0009611 IEA response to wounding
GO:0010033 IEA response to organic substance
GO:0010460 IEA positive regulation of heart rate
GO:0019933 IEA cAMP-mediated signaling
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0031100 IEA organ regeneration
GO:0031102 IEA neuron projection regeneration
GO:0031623 IEA receptor internalization
GO:0031700 IEA adrenomedullin receptor binding
GO:0032496 IEA response to lipopolysaccharide
GO:0032868 IEA response to insulin
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0042594 IEA response to starvation
GO:0043065 IEA positive regulation of apoptotic process
GO:0043116 IMP negative regulation of vascular permeability
GO:0045766 IMP positive regulation of angiogenesis
GO:0045906 IEA negative regulation of vasoconstriction
GO:0045909 IEA positive regulation of vasodilation
GO:0046879 IEA hormone secretion
GO:0048589 IMP developmental growth
GO:0051384 IEA response to glucocorticoid
GO:0055074 IEA calcium ion homeostasis
GO:0060670 IMP branching involved in labyrinthine layer morphogenesis
GO:0060712 IMP spongiotrophoblast layer development
GO:0097084 IMP vascular smooth muscle cell development
GO:2001214 IMP positive regulation of vasculogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015263 adma adrenomedullin a protein_coding Danio_rerio
ENSG00000148926 ADM adrenomedullin protein_coding Homo_sapiens

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