C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: A kinase (PRKA) anchor protein 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151320 AKAP6 9606 + 14:32329273-32837681 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000280979 AKAP6-001 32329273-32837681 protein_coding
  ENST00000553547 AKAP6-003 32473757-32546449 protein_coding
  ENST00000554410 AKAP6-008 32494271-32545455 protein_coding
  ENST00000554449 AKAP6-006 32433164-32439032 processed_transcript
  ENST00000554740 AKAP6-015 32735851-32774001 protein_coding
  ENST00000555207 AKAP6-010 32616967-32773791 processed_transcript
  ENST00000555950 AKAP6-011 32616978-32732765 processed_transcript
  ENST00000556037 AKAP6-007 32329350-32433982 retained_intron
  ENST00000556540 AKAP6-014 32733262-32773829 processed_transcript
  ENST00000556638 AKAP6-009 32495072-32545520 protein_coding
  ENST00000557102 AKAP6-005 32329349-32433817 protein_coding
  ENST00000557272 AKAP6-004 32329400-32830817 protein_coding
  ENST00000557354 AKAP6-002 32329344-32734613 protein_coding
  ENST00000557396 AKAP6-013 32693401-32732584 processed_transcript
  ENST00000557708 AKAP6-012 32693462-32735725 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000280979ENST00000557272ENST00000557354
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000280979 N/A N/A N/A 2.493±0.98 N/A N/A 1.798±0.33 N/A N/A N/A N/A 0.058±0.00 N/A 0.334±0.00
ENST00000557272 0.198±0.00 0.594±0.00 1.106±0.00 12.469±0.03 0.836±0.15 1.441±0.01 8.659±0.00 0.455±0.17 2.707±2.66 0.930±0.31 11.683±0.65 0.255±0.15 0.313±0.21 1.747±0.00
ENST00000557354 N/A N/A N/A N/A N/A N/A N/A N/A 1.679±0.00 0.697±0.25 N/A 0.138±0.00 0.147±0.08 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000H7 CIL_0000H7_0001 CGP 14:32076114-32837681
CIL_0007W5 CIL_0007W5_0001 VISTA 14:32170844-32774888
CIL_0005RB CIL_0005RB_0002 CGP 14:32329273-33804176

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001508 IC action potential
GO:0005515 IPI protein binding
GO:0005635 IDA nuclear envelope
GO:0005737 ISS cytoplasm
GO:0005901 ISS caveola
GO:0006605 NAS protein targeting
GO:0008179 ISS adenylate cyclase binding
GO:0010738 ISS regulation of protein kinase A signaling
GO:0010880 IC regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0014701 ISS junctional sarcoplasmic reticulum membrane
GO:0014704 ISS intercalated disc
GO:0016529 IDA sarcoplasmic reticulum
GO:0019933 NAS cAMP-mediated signaling
GO:0030307 ISS positive regulation of cell growth
GO:0030315 ISS T-tubule
GO:0030818 ISS negative regulation of cAMP biosynthetic process
GO:0032514 ISS positive regulation of protein phosphatase type 2B activity
GO:0032947 ISS protein complex scaffold
GO:0034237 ISS protein kinase A regulatory subunit binding
GO:0034704 IDA calcium channel complex
GO:0043495 ISS protein anchor
GO:0044325 IPI ion channel binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051018 NAS protein kinase A binding
GO:0051281 ISS positive regulation of release of sequestered calcium ion into cytosol
GO:0051533 ISS positive regulation of NFAT protein import into nucleus
GO:0060306 IDA regulation of membrane repolarization
GO:0060316 ISS positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0061051 ISS positive regulation of cell growth involved in cardiac muscle cell development
GO:0070886 ISS positive regulation of calcineurin-NFAT signaling cascade
GO:0071320 IDA cellular response to cAMP
GO:0071345 ISS cellular response to cytokine stimulus
GO:1901381 IDA positive regulation of potassium ion transmembrane transport
GO:1902261 IDA positive regulation of delayed rectifier potassium channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077295 akap6 A kinase (PRKA) anchor protein 6 protein_coding Danio_rerio
ENSMUSG00000061603 Akap6 A kinase (PRKA) anchor protein 6 protein_coding Mus_musculus

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