C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDK2-associated, cullin domain 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151893 CACUL1 9606 - 10:118674167-118755249 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000369151 CACUL1-001 118676411-118755246 protein_coding
  ENST00000477583 CACUL1-004 118729175-118754477 retained_intron
  ENST00000481360 CACUL1-005 118694921-118707513 retained_intron
  ENST00000489169 CACUL1-006 118685997-118691565 retained_intron
  ENST00000490610 CACUL1-007 118685959-118686781 retained_intron
  ENST00000493518 CACUL1-002 118684556-118755249 nonsense_mediated_decay
  ENST00000544392 CACUL1-008 118674167-118726385 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369151ENST00000489169ENST00000493518
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369151 1.417±0.00 1.347±0.00 1.017±0.00 1.893±0.39 2.907±1.51 0.870±0.00 0.659±0.00 0.979±0.03 1.781±0.71 2.494±0.25 1.220±0.67 2.032±0.81 1.400±0.10 3.511±1.63
ENST00000489169 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 27.553±0.00
ENST00000493518 3.377±0.00 N/A 2.010±0.00 2.369±0.73 4.713±0.00 4.237±0.00 2.347±0.85 N/A 6.172±0.00 2.706±0.00 2.372±0.28 8.724±0.00 N/A 4.734±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002T8 CIL_0002T8_0001 CGP 10:118589989-118755249
CIL_00062M CIL_00062M_0001 CGP 10:118674167-119033732

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0005515 IPI protein binding
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008284 IMP positive regulation of cell proliferation
GO:0019901 IPI protein kinase binding
GO:0031461 IEA cullin-RING ubiquitin ligase complex
GO:0031625 IEA ubiquitin protein ligase binding
GO:0045860 IMP positive regulation of protein kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021885 CACUL1 CDK2-associated, cullin domain 1 protein_coding Danio_rerio
ENSMUSG00000033417 Cacul1 CDK2 associated, cullin domain 1 protein_coding Mus_musculus

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