C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: POU class 4 homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152192 POU4F1 9606 - 13:78598362-78603560 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377208 POU4F1-001 78598362-78603560 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartLungMuscleOvaryPlacentaTestisENST00000377208
Transcript ID Adrenal Brain Breast Colon Heart Lung Muscle Ovary Placenta Testis
ENST00000377208 0.009±0.00 0.046±0.00 0.006±0.00 0.017±0.00 0.021±0.00 0.031±0.00 0.053±0.00 0.044±0.04 0.044±0.01 1.372±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000U0 CIL_0000U0_0001 CGP 13:77895481-78603560
CIL_00097M CIL_00097M_0001 VISTA 13:78101880-78703203
CIL_0007M3 CIL_0007M3_0001 UCNEbase 13:78239925-79269621
CIL_0000U2 CIL_0000U2_0001 CGP 13:78598362-78659179

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0000980 ISS RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001205 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001967 IEA suckling behavior
GO:0003223 IEA ventricular compact myocardium morphogenesis
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003705 ISS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0007399 IEA nervous system development
GO:0007409 TAS axonogenesis
GO:0007416 TAS synapse assembly
GO:0007498 IEA mesoderm development
GO:0021535 IEA cell migration in hindbrain
GO:0021559 ISS trigeminal nerve development
GO:0021953 IEA central nervous system neuron differentiation
GO:0021986 IEA habenula development
GO:0030182 IEA neuron differentiation
GO:0043005 IEA neuron projection
GO:0043065 IEA positive regulation of apoptotic process
GO:0043524 TAS negative regulation of neuron apoptotic process
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048665 ISS neuron fate specification
GO:0048880 ISS sensory system development
GO:0048934 IEA peripheral nervous system neuron differentiation
GO:0048935 ISS peripheral nervous system neuron development
GO:0050767 IEA regulation of neurogenesis
GO:0051355 IEA proprioception involved in equilibrioception
GO:0060384 TAS innervation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005559 pou4f1 POU domain, class 4, transcription factor 1 protein_coding Danio_rerio
ENSMUSG00000048349 Pou4f1 POU domain, class 4, transcription factor 1 protein_coding Mus_musculus

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