C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: POU domain, class 4, transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000048349 Pou4f1 10090 - 14:104461676-104467999 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000053016 Pou4f1-001 104461676-104467999 protein_coding
  ENSMUST00000139505 Pou4f1-002 104463973-104465365 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000053016ENSMUST00000139505
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000053016 0.010±0.00 0.096±0.05 0.027±0.01 4.451±3.14 0.067±0.03 0.091±0.02 0.028±0.00 0.026±0.01 0.009±0.00 0.042±0.01 0.166±0.06 0.428±0.22 0.038±0.02 0.189±0.10
ENSMUST00000139505 N/A N/A N/A 0.509±0.00 N/A N/A 0.049±0.00 0.061±0.00 0.016±0.01 N/A 0.418±0.19 0.443±0.15 0.135±0.14 0.814±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000U0 CIL_0000U0_0002 CGP 14:103814625-104467999
CIL_00081V CIL_00081V_0002 VISTA 14:103890395-104491968
CIL_00097M CIL_00097M_0002 VISTA 14:103997360-104598672
CIL_0007M3 CIL_0007M3_0002 UCNEbase 14:104145568-105070718
CIL_0000U2 CIL_0000U2_0002 CGP 14:104461676-104522666

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001205 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001967 IMP suckling behavior
GO:0003223 IMP ventricular compact myocardium morphogenesis
GO:0003677 IDA DNA binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0003705 IC RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006366 IC transcription from RNA polymerase II promoter
GO:0007399 IDA nervous system development
GO:0007498 IMP mesoderm development
GO:0021535 IMP cell migration in hindbrain
GO:0021559 IMP trigeminal nerve development
GO:0021953 IMP central nervous system neuron differentiation
GO:0021986 IMP habenula development
GO:0030182 IMP neuron differentiation
GO:0043005 IDA neuron projection
GO:0043065 IGI positive regulation of apoptotic process
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048665 IMP neuron fate specification
GO:0048880 IMP sensory system development
GO:0048934 IMP peripheral nervous system neuron differentiation
GO:0048935 IMP peripheral nervous system neuron development
GO:0050767 IMP regulation of neurogenesis
GO:0051355 IMP proprioception involved in equilibrioception
GO:0060384 IMP innervation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005559 pou4f1 POU domain, class 4, transcription factor 1 protein_coding Danio_rerio
ENSG00000152192 POU4F1 POU class 4 homeobox 1 protein_coding Homo_sapiens

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