C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152527 PLEKHH2 9606 + 2:43637273-43767987 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282406 PLEKHH2-001 43637273-43767987 protein_coding
  ENST00000405000 PLEKHH2-002 43637308-43765792 retained_intron
  ENST00000405223 PLEKHH2-003 43637300-43741365 retained_intron
  ENST00000460356 PLEKHH2-005 43692230-43695204 retained_intron
  ENST00000480103 PLEKHH2-008 43731541-43743870 retained_intron
  ENST00000490038 PLEKHH2-007 43745899-43765482 nonsense_mediated_decay
  ENST00000491692 PLEKHH2-004 43637339-43697239 nonsense_mediated_decay
  ENST00000493408 PLEKHH2-006 43740985-43744134 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000282406ENST00000405000ENST00000405223ENST00000493408
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000282406 1.037±0.00 0.327±0.00 0.325±0.09 1.479±0.10 1.612±0.00 0.142±0.00 0.809±0.00 0.776±0.70 6.075±1.23 0.056±0.02 2.092±1.11 0.418±0.16 1.324±0.13
ENST00000405000 N/A N/A 0.093±0.00 N/A 0.301±0.00 0.071±0.00 N/A 0.877±0.00 N/A 0.033±0.00 0.851±0.41 0.149±0.00 0.545±0.00
ENST00000405223 N/A N/A N/A N/A 1.363±0.00 N/A 0.644±0.00 1.114±0.00 6.458±0.00 N/A 1.412±0.00 N/A N/A
ENST00000493408 N/A N/A 3.120±0.00 N/A 7.401±0.00 N/A N/A N/A N/A 0.452±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GQ CIL_0000GQ_0001 CGP 2:43230836-43767987
CIL_0004BS CIL_0004BS_0001 CGP 2:43637273-43810010

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 ISS actin binding
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0030027 IDA lamellipodium
GO:0030835 ISS negative regulation of actin filament depolymerization
GO:0030864 ISS cortical actin cytoskeleton
GO:0042802 IEA identical protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040851 plekhh2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 protein_coding Danio_rerio
ENSMUSG00000040852 Plekhh2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 protein_coding Mus_musculus

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