C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphofructokinase, muscle
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152556 PFKM 9606 + 12:48105139-48146404 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000312352 PFKM-201 48122647-48146404 protein_coding
  ENST00000340802 PFKM-001 48105923-48146104 protein_coding
  ENST00000359794 PFKM-002 48119226-48146404 protein_coding
  ENST00000546465 PFKM-020 48122720-48142813 protein_coding
  ENST00000546755 PFKM-012 48106107-48122841 protein_coding
  ENST00000546964 PFKM-004 48119343-48146104 retained_intron
  ENST00000547066 PFKM-015 48119264-48131383 nonsense_mediated_decay
  ENST00000547148 PFKM-026 48137357-48141316 retained_intron
  ENST00000547581 PFKM-003 48106106-48146104 nonsense_mediated_decay
  ENST00000547587 PFKM-005 48122647-48146104 protein_coding
  ENST00000548288 PFKM-029 48106388-48131368 protein_coding
  ENST00000548345 PFKM-019 48119391-48134829 protein_coding
  ENST00000548720 PFKM-016 48119348-48131719 retained_intron
  ENST00000549003 PFKM-009 48105482-48132980 protein_coding
  ENST00000549022 PFKM-014 48122574-48133370 protein_coding
  ENST00000549366 PFKM-007 48106116-48131342 protein_coding
  ENST00000549941 PFKM-010 48105911-48132989 protein_coding
  ENST00000550257 PFKM-011 48105923-48131381 protein_coding
  ENST00000550345 PFKM-008 48105139-48133360 protein_coding
  ENST00000550802 PFKM-027 48141338-48144073 retained_intron
  ENST00000550924 PFKM-028 48105621-48132884 protein_coding
  ENST00000551339 PFKM-030 48119364-48133049 protein_coding
  ENST00000551485 PFKM-018 48119352-48133320 nonsense_mediated_decay
  ENST00000551548 PFKM-017 48119352-48131920 processed_transcript
  ENST00000551804 PFKM-006 48119787-48146104 protein_coding
  ENST00000552214 PFKM-023 48141672-48142897 retained_intron
  ENST00000552752 PFKM-025 48137791-48142866 nonsense_mediated_decay
  ENST00000552792 PFKM-013 48106144-48131392 protein_coding
  ENST00000552818 PFKM-022 48141705-48142378 retained_intron
  ENST00000552989 PFKM-021 48119351-48137815 nonsense_mediated_decay
  ENST00000553055 PFKM-024 48141973-48145051 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000312352ENST00000340802ENST00000359794ENST00000546964ENST00000547587ENST00000551804
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000312352 N/A N/A N/A N/A N/A 1.600±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000340802 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 21.624±0.00
ENST00000359794 N/A N/A N/A 7.286±0.00 3.019±0.00 N/A 6.171±0.00 N/A N/A 1.814±0.00 N/A 3.528±0.00 N/A N/A
ENST00000546964 N/A 5.049±0.00 4.570±0.00 9.533±2.08 4.939±0.00 4.798±0.00 6.578±0.00 4.204±3.34 7.240±0.00 2.213±0.39 N/A 6.527±2.85 N/A 15.148±0.00
ENST00000547587 4.061±0.00 N/A 5.354±0.00 N/A 10.426±0.00 4.802±0.38 31.738±17.18 N/A 1.976±0.87 6.077±0.00 160.608±71.03 14.846±10.72 11.419±1.43 53.614±0.00
ENST00000551804 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.813±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00079B CIL_00079B_0001 CGP 12:47972965-48106308
CIL_00068J CIL_00068J_0001 CGP 12:48042898-48146404
CIL_00068I CIL_00068I_0001 CGP 12:48105139-48181213

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003872 IEA:ISS 6-phosphofructokinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005945 IDA 6-phosphofructokinase complex
GO:0005975 TAS carbohydrate metabolic process
GO:0006002 IEA:IMP fructose 6-phosphate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006096 IEA glycolytic process
GO:0008022 IPI protein C-terminus binding
GO:0008443 IEA phosphofructokinase activity
GO:0016324 IDA apical plasma membrane
GO:0019900 IPI kinase binding
GO:0032024 IEA positive regulation of insulin secretion
GO:0042593 IEA glucose homeostasis
GO:0042802 IPI identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0046716 IMP muscle cell cellular homeostasis
GO:0046835 IEA carbohydrate phosphorylation
GO:0046872 IEA metal ion binding
GO:0051259 IDA protein oligomerization
GO:0070061 IDA fructose binding
GO:0070062 IDA extracellular vesicular exosome
GO:0097228 IEA sperm principal piece

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014179 pfkma phosphofructokinase, muscle a protein_coding Danio_rerio
ENSDARG00000060797 pfkmb phosphofructokinase, muscle b protein_coding Danio_rerio
ENSMUSG00000033065 Pfkm phosphofructokinase, muscle protein_coding Mus_musculus

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