C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphofructokinase, muscle
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033065 Pfkm 10090 + 15:98092589-98132447 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000051226 Pfkm-201 98108471-98132447 protein_coding
  ENSMUST00000163507 Pfkm-202 98092589-98132447 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000051226ENSMUST00000163507
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000051226 16.755±2.92 13.906±4.24 37.961±0.53 85.110±61.52 36.693±32.85 7.959±1.77 279.953±18.52 24.761±3.90 6.468±1.56 17.379±3.23 593.963±120.83 22.478±4.64 10.176±5.75 15.264±6.15
ENSMUST00000163507 N/A 12.675±4.99 N/A N/A 53.281±29.43 2.721±0.00 N/A N/A 11.116±8.94 10.814±0.00 615.881±220.15 10.576±6.27 6.042±0.00 38.212±9.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00079B CIL_00079B_0002 CGP 15:97975602-98093744
CIL_00068J CIL_00068J_0002 CGP 15:98038744-98132447
CIL_00068I CIL_00068I_0002 CGP 15:98092589-98165625

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003872 ISS 6-phosphofructokinase activity
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0005945 IEA 6-phosphofructokinase complex
GO:0006002 IEA fructose 6-phosphate metabolic process
GO:0006096 IMP glycolytic process
GO:0008022 IEA protein C-terminus binding
GO:0008443 IDA phosphofructokinase activity
GO:0016324 IEA apical plasma membrane
GO:0019900 IEA kinase binding
GO:0032024 IMP positive regulation of insulin secretion
GO:0042593 IMP glucose homeostasis
GO:0042802 IEA identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0046716 IEA muscle cell cellular homeostasis
GO:0046835 IEA carbohydrate phosphorylation
GO:0046872 IEA metal ion binding
GO:0051259 IEA protein oligomerization
GO:0061615 IC glycolytic process through fructose-6-phosphate
GO:0070061 IEA fructose binding
GO:0070062 IEA extracellular vesicular exosome
GO:0097228 IDA sperm principal piece

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014179 pfkma phosphofructokinase, muscle a protein_coding Danio_rerio
ENSDARG00000060797 pfkmb phosphofructokinase, muscle b protein_coding Danio_rerio
ENSG00000152556 PFKM phosphofructokinase, muscle protein_coding Homo_sapiens

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