C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3 domain containing ring finger 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154447 SH3RF1 9606 - 4:169094256-169271105 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000284637 SH3RF1-001 169094256-169271105 protein_coding
  ENST00000502315 SH3RF1-004 169268914-169270849 protein_coding
  ENST00000508685 SH3RF1-003 169116269-169269093 processed_transcript
  ENST00000510806 SH3RF1-005 169268976-169269957 protein_coding
  ENST00000511421 SH3RF1-002 169116269-169156657 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000284637ENST00000508685
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000284637 5.094±0.00 0.736±0.00 2.105±0.00 4.282±1.40 2.400±0.02 2.762±0.42 1.106±0.68 5.887±0.00 0.244±0.00 3.473±1.04 5.233±0.00 4.090±1.08 3.031±1.87 3.192±0.77
ENST00000508685 N/A N/A 1.659±0.00 3.051±0.00 N/A N/A N/A 1.253±0.00 N/A 1.672±0.00 N/A 5.042±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005794 IEA Golgi apparatus
GO:0005829 IDA cytosol
GO:0006915 IEA apoptotic process
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0042995 IEA cell projection
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0046328 IEA regulation of JNK cascade
GO:0046872 IEA metal ion binding
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070470 sh3rf1 SH3 domain containing ring finger 1 protein_coding Danio_rerio
ENSMUSG00000031642 Sh3rf1 SH3 domain containing ring finger 1 protein_coding Mus_musculus

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