C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ADAM metallopeptidase with thrombospondin type 1 motif, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154734 ADAMTS1 9606 - 21:26835747-26845409 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000284984 ADAMTS1-001 26835747-26845409 protein_coding
  ENST00000451462 ADAMTS1-003 26841120-26843540 protein_coding
  ENST00000464589 ADAMTS1-002 26836287-26841711 retained_intron
  ENST00000492656 ADAMTS1-004 26838093-26840489 retained_intron
  ENST00000517452 ADAMTS1-006 26841969-26843777 protein_coding
  ENST00000517777 ADAMTS1-007 26841077-26843018 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000284984ENST00000451462ENST00000464589ENST00000517777
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000284984 19.255±0.00 12.356±0.00 2.352±0.00 2.315±0.00 6.369±0.51 6.135±4.17 3.064±1.28 3.025±2.86 2.608±1.99 20.311±0.00 4.196±0.17 20.515±12.82 63.177±43.96 4.295±0.80
ENST00000451462 N/A N/A 6.273±0.00 N/A N/A N/A 4.674±0.00 1.314±0.00 N/A N/A N/A N/A N/A N/A
ENST00000464589 N/A N/A N/A 0.450±0.00 1.376±0.00 0.912±0.00 N/A N/A 2.477±0.00 2.640±0.00 N/A 1.095±0.00 N/A 2.334±0.00
ENST00000517777 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.823±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000335 CIL_000335_0001 CGP 21:26466209-26845409
CIL_0008UA CIL_0008UA_0001 VISTA 21:26654008-27255434
CIL_00032M CIL_00032M_0001 CGP 21:26835747-26966513

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001542 IEA ovulation from ovarian follicle
GO:0001822 IEA kidney development
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IEA protein binding
GO:0005604 IEA basement membrane
GO:0005737 IDA cytoplasm
GO:0006508 IEA proteolysis
GO:0007229 TAS integrin-mediated signaling pathway
GO:0008201 IEA heparin binding
GO:0008237 TAS metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0008285 TAS negative regulation of cell proliferation
GO:0031012 IEA extracellular matrix
GO:0031410 IEA cytoplasmic vesicle
GO:0060347 IEA heart trabecula formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041566 adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 protein_coding Danio_rerio
ENSMUSG00000022893 Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 protein_coding Mus_musculus

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