C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022893 Adamts1 10090 - 16:85793827-85803113 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023610 Adamts1-001 85793827-85803113 protein_coding
  ENSMUST00000125897 Adamts1-002 85795476-85801481 protein_coding
  ENSMUST00000138474 Adamts1-003 85798231-85799638 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023610ENSMUST00000125897ENSMUST00000138474
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023610 19.042±8.59 9.658±0.34 12.021±2.65 2.329±0.63 8.609±2.75 2.864±0.29 5.145±1.49 10.792±2.27 3.332±1.35 32.361±2.89 5.080±0.93 18.114±8.96 7.223±3.32 0.259±0.08
ENSMUST00000125897 N/A N/A N/A N/A 5.806±0.00 N/A 2.965±0.66 2.956±0.00 N/A N/A 2.121±0.00 N/A 2.883±0.00 0.225±0.10
ENSMUST00000138474 35.963±2.09 N/A N/A N/A 6.704±1.22 2.092±0.00 N/A N/A 3.076±0.00 N/A N/A N/A N/A 0.687±0.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000335 CIL_000335_0002 CGP 16:85421533-85803113
CIL_0008UA CIL_0008UA_0002 VISTA 16:85587133-86188622
CIL_00032M CIL_00032M_0002 CGP 16:85793827-85901125

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001542 IMP ovulation from ovarian follicle
GO:0001822 IMP kidney development
GO:0004222 IDA metalloendopeptidase activity
GO:0005515 IPI protein binding
GO:0005604 IDA basement membrane
GO:0005737 IEA cytoplasm
GO:0006508 IEA proteolysis
GO:0008201 IDA heparin binding
GO:0008270 IEA zinc ion binding
GO:0016525 ISO negative regulation of angiogenesis
GO:0031012 IDA extracellular matrix
GO:0031410 IDA cytoplasmic vesicle
GO:0060347 IMP heart trabecula formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041566 adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 protein_coding Danio_rerio
ENSG00000154734 ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 protein_coding Homo_sapiens

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