C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: formin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000155816 FMN2 9606 + 1:240014348-240475189 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000319653 FMN2-001 240091880-240475189 protein_coding
  ENST00000441342 FMN2-005 240245260-240329392 protein_coding
  ENST00000447095 FMN2-003 240014348-240207187 protein_coding
  ENST00000463398 FMN2-004 240235771-240330676 processed_transcript
  ENST00000496950 FMN2-002 240472098-240474709 processed_transcript
  ENST00000543681 FMN2-201 240457482-240474267 protein_coding
  ENST00000545751 FMN2-202 240329144-240475183 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000319653ENST00000441342ENST00000447095ENST00000463398ENST00000496950ENST00000543681ENST00000545751
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000319653 0.026±0.00 0.099±0.00 0.027±0.00 7.827±6.53 0.049±0.02 1.056±0.00 0.755±0.00 0.076±0.00 0.028±0.00 0.414±0.22 0.029±0.01 0.617±0.16
ENST00000441342 0.354±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000447095 N/A N/A N/A N/A 0.512±0.00 N/A N/A N/A N/A 0.028±0.00 N/A N/A
ENST00000463398 N/A N/A N/A N/A N/A N/A N/A N/A 0.437±0.00 N/A N/A N/A
ENST00000496950 0.111±0.00 N/A 0.571±0.00 N/A N/A N/A N/A N/A N/A N/A 0.132±0.00 N/A
ENST00000543681 N/A N/A 0.095±0.00 N/A N/A N/A N/A 0.006±0.00 N/A N/A N/A N/A
ENST00000545751 0.124±0.00 0.039±0.00 0.069±0.00 4.323±0.00 N/A 1.335±0.00 N/A N/A 0.051±0.00 0.535±0.00 0.081±0.03 0.719±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KG CIL_0006KG_0001 CGP 1:240014348-240612149

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0003779 IDA actin binding
GO:0005575 ND cellular_component
GO:0005730 IDA nucleolus
GO:0005783 IEA endoplasmic reticulum
GO:0005789 IEA endoplasmic reticulum membrane
GO:0005819 IEA spindle
GO:0005829 IDA cytosol
GO:0005884 IEA actin filament
GO:0005886 IEA plasma membrane
GO:0005902 IEA microvillus
GO:0005938 ISS cell cortex
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0007275 IEA multicellular organismal development
GO:0015031 IEA protein transport
GO:0015629 IDA actin cytoskeleton
GO:0016192 ISS vesicle-mediated transport
GO:0016344 IEA meiotic chromosome movement towards spindle pole
GO:0030659 ISS cytoplasmic vesicle membrane
GO:0035556 IEA intracellular signal transduction
GO:0040038 ISS polar body extrusion after meiotic divisions
GO:0042177 IMP negative regulation of protein catabolic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0045010 IEA actin nucleation
GO:0046907 ISS intracellular transport
GO:0048477 ISS oogenesis
GO:0051017 IEA actin filament bundle assembly
GO:0051295 ISS establishment of meiotic spindle localization
GO:0051758 ISS homologous chromosome movement towards spindle pole involved in homologous chromosome segregation
GO:0070649 ISS formin-nucleated actin cable assembly
GO:0071456 IMP cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023318 fmn2a formin 2a protein_coding Danio_rerio
ENSDARG00000061778 fmn2b formin 2b protein_coding Danio_rerio
ENSMUSG00000028354 Fmn2 formin 2 protein_coding Mus_musculus

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