C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MX dynamin-like GTPase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000398598 MX1-002 ENSG00000157601 9606 + 21:41426167-41459214 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000398598
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000398598 3.692±0.00 7.164±0.00 3.935±0.79 5.481±0.81 2.660±1.18 4.601±1.35 4.696±0.47 0.761±0.01 9.711±2.55 1.765±0.26 24.821±7.93 27.926±8.30 5.626±1.63

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CV CIL_0001CV_0004 CGP 21:41361943-41459214

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005829 IDA cytosol
GO:0006184 IEA GTP catabolic process
GO:0006915 TAS apoptotic process
GO:0006952 TAS defense response
GO:0007165 TAS signal transduction
GO:0009615 IMP response to virus
GO:0016020 IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0034340 TAS response to type I interferon
GO:0045071 IDA negative regulation of viral genome replication
GO:0045087 TAS innate immune response
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051607 IEA defense response to virus
GO:0060337 TAS type I interferon signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023655 Mx1-201 protein_coding Mus_musculus 1e-30 139
ENSMUST00000113768 Mx1-001 protein_coding Mus_musculus 1e-30 139
ENSMUST00000155233 Mx1-003 nonsense_mediated_decay Mus_musculus 1e-30 139
ENSMUST00000135184 Mx1-002 nonsense_mediated_decay Mus_musculus 1e-30 139

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