C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: diacylglycerol kinase, iota
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157680 DGKI 9606 - 7:137381037-137847092 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000288490 DGKI-001 137390524-137846863 protein_coding
  ENST00000424189 DGKI-014 137390524-137847092 protein_coding
  ENST00000446122 DGKI-003 137390524-137847092 protein_coding
  ENST00000453654 DGKI-002 137381037-137846536 protein_coding
  ENST00000460662 DGKI-005 137463489-137581928 processed_transcript
  ENST00000470895 DGKI-008 137585261-137847092 processed_transcript
  ENST00000475388 DGKI-010 137771599-137774649 processed_transcript
  ENST00000477835 DGKI-012 137391038-137454873 processed_transcript
  ENST00000483619 DGKI-009 137678607-137774990 processed_transcript
  ENST00000486153 DGKI-013 137391085-137395973 retained_intron
  ENST00000494390 DGKI-006 137388817-137453194 processed_transcript
  ENST00000497321 DGKI-011 137391155-137466035 processed_transcript
  ENST00000614521 DGKI-201 137391220-137690004 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000288490ENST00000424189ENST00000453654ENST00000460662ENST00000494390ENST00000497321ENST00000614521
Transcript ID Adipose Brain Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000288490 N/A N/A 0.125±0.00 N/A N/A N/A N/A 0.120±0.00 N/A N/A
ENST00000424189 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.429±0.00
ENST00000453654 N/A N/A 0.101±0.00 N/A 0.002±0.00 N/A 0.016±0.00 N/A 0.011±0.00 N/A
ENST00000460662 N/A 12.187±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000494390 0.017±0.00 N/A N/A 0.082±0.00 0.018±0.00 0.066±0.00 N/A 0.079±0.00 0.029±0.00 0.091±0.00
ENST00000497321 N/A N/A N/A 0.236±0.00 N/A N/A N/A N/A N/A N/A
ENST00000614521 0.074±0.00 5.238±0.00 N/A N/A N/A N/A N/A 0.058±0.00 N/A 0.352±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002Q6 CIL_0002Q6_0001 CGP 7:137227341-137847092

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0005095 IEA GTPase inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 TAS cytoplasm
GO:0005886 TAS plasma membrane
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0016310 IEA phosphorylation
GO:0017016 IEA Ras GTPase binding
GO:0030168 TAS platelet activation
GO:0032045 IEA guanyl-nucleotide exchange factor complex
GO:0032317 IEA regulation of Rap GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0043086 IEA negative regulation of catalytic activity
GO:0046579 IEA positive regulation of Ras protein signal transduction
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063578 DGKI diacylglycerol kinase, iota protein_coding Danio_rerio
ENSMUSG00000038665 Dgki diacylglycerol kinase, iota protein_coding Mus_musculus

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