C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: diacylglycerol kinase, iota
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038665 Dgki 10090 - 6:36846022-37300184 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042075 Dgki-002 36847156-37299637 protein_coding
  ENSMUST00000090314 Dgki-005 36846981-37300184 protein_coding
  ENSMUST00000101532 Dgki-001 36846022-37299974 protein_coding
  ENSMUST00000136457 Dgki-007 37231044-37299744 processed_transcript
  ENSMUST00000138286 Dgki-004 36846981-37300184 nonsense_mediated_decay
  ENSMUST00000143046 Dgki-006 36911467-37031028 processed_transcript
  ENSMUST00000146656 Dgki-008 37034608-37064510 processed_transcript
  ENSMUST00000150300 Dgki-003 36846981-37300184 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042075ENSMUST00000090314ENSMUST00000101532ENSMUST00000136457ENSMUST00000138286ENSMUST00000143046ENSMUST00000150300
Transcript ID Adipose Adrenal Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042075 N/A N/A 2.384±0.00 N/A 0.062±0.00 0.025±0.02 0.020±0.01 N/A 0.018±0.00 0.126±0.07 0.022±0.00 0.075±0.00
ENSMUST00000090314 0.504±0.15 0.204±0.04 N/A 0.486±0.00 N/A N/A 0.033±0.01 0.027±0.01 N/A 0.150±0.10 N/A 0.067±0.04
ENSMUST00000101532 0.138±0.14 0.348±0.21 1.559±0.00 0.201±0.09 0.019±0.01 0.026±0.00 0.010±0.00 0.051±0.02 0.005±0.00 0.207±0.10 0.035±0.00 0.078±0.04
ENSMUST00000136457 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.492±0.00 N/A N/A
ENSMUST00000138286 N/A N/A N/A 0.122±0.00 N/A N/A N/A 0.052±0.00 N/A 0.071±0.05 N/A N/A
ENSMUST00000143046 N/A N/A N/A N/A 0.009±0.00 N/A 0.014±0.00 N/A 0.024±0.00 0.152±0.12 N/A N/A
ENSMUST00000150300 0.026±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002Q6 CIL_0002Q6_0002 CGP 6:36715663-37300184
CIL_00011O CIL_00011O_0002 CGP 6:36846022-37442146

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IDA diacylglycerol kinase activity
GO:0005095 IDA GTPase inhibitor activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016310 IEA phosphorylation
GO:0017016 IPI Ras GTPase binding
GO:0032045 IDA guanyl-nucleotide exchange factor complex
GO:0032317 IMP regulation of Rap GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0043086 IDA negative regulation of catalytic activity
GO:0046579 IMP positive regulation of Ras protein signal transduction
GO:0048471 IDA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063578 DGKI diacylglycerol kinase, iota protein_coding Danio_rerio
ENSG00000157680 DGKI diacylglycerol kinase, iota protein_coding Homo_sapiens

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