C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement component 1, r subcomponent
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159403 C1R 9606 - 12:7080209-7092607 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000535233 C1R-003 7080421-7092472 protein_coding
  ENST00000536053 C1R-004 7080421-7091892 protein_coding
  ENST00000536092 C1R-008 7091156-7092493 retained_intron
  ENST00000538050 C1R-013 7089696-7091891 protein_coding
  ENST00000540242 C1R-009 7089655-7092493 protein_coding
  ENST00000540394 C1R-002 7080214-7092441 retained_intron
  ENST00000540610 C1R-006 7089465-7092540 protein_coding
  ENST00000541042 C1R-007 7089628-7092493 protein_coding
  ENST00000542285 C1R-001 7080209-7092607 protein_coding
  ENST00000543362 C1R-012 7089358-7092430 nonsense_mediated_decay
  ENST00000543835 C1R-011 7089615-7092441 protein_coding
  ENST00000543851 C1R-014 7089648-7090358 retained_intron
  ENST00000545466 C1R-010 7089936-7092441 retained_intron
  ENST00000602298 C1R-015 7080419-7087844 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000535233ENST00000536053ENST00000542285
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000535233 121.580±0.00 181.820±0.00 N/A 5.422±0.00 43.121±12.90 70.449±61.18 32.735±29.33 99.835±26.50 264.952±228.57 71.879±52.51 11.911±6.99 46.701±31.91 23.919±0.00 79.440±52.25
ENST00000536053 219.436±0.00 176.893±0.00 10.694±0.00 4.560±2.83 37.739±23.49 76.931±68.41 13.888±10.74 76.089±29.54 120.471±106.68 33.138±20.03 8.650±5.89 152.665±129.76 44.711±8.95 84.192±61.86
ENST00000542285 98.812±0.00 N/A N/A 2.871±2.22 17.149±0.00 49.690±41.98 17.562±15.78 72.752±25.24 10.603±0.00 41.346±0.00 6.587±0.00 266.969±269.84 15.635±5.60 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00001H CIL_00001H_0001 CGP 12:6988259-7092607

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005576 NAS extracellular region
GO:0006508 IEA proteolysis
GO:0006955 TAS immune response
GO:0006956 TAS complement activation
GO:0006958 TAS complement activation, classical pathway
GO:0008236 TAS serine-type peptidase activity
GO:0045087 TAS innate immune response
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000055172 C1ra complement component 1, r subcomponent A protein_coding Mus_musculus
ENSMUSG00000098470 C1rb complement component 1, r subcomponent B protein_coding Mus_musculus

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