C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mediator complex subunit 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159479 MED8 9606 - 1:43383917-43389808 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290663 MED8-002 43383917-43389808 protein_coding
  ENST00000372455 MED8-001 43384726-43389784 protein_coding
  ENST00000372457 MED8-007 43383969-43389808 protein_coding
  ENST00000460803 MED8-005 43385673-43386931 retained_intron
  ENST00000473560 MED8-006 43385978-43387647 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000290663ENST00000372455ENST00000372457ENST00000460803ENST00000473560
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000290663 4.845±0.00 3.601±0.00 0.950±0.00 3.072±0.00 7.049±0.00 3.885±0.23 N/A 5.701±0.85 5.128±0.00 5.854±0.00 1.889±0.28 4.216±1.78 6.541±3.39 4.838±0.00
ENST00000372455 3.646±0.00 3.665±0.00 N/A 4.930±0.00 3.163±1.64 N/A 2.473±0.00 N/A 4.889±0.00 5.403±0.00 2.870±0.00 5.904±0.00 6.343±1.38 5.793±0.04
ENST00000372457 6.034±0.00 6.142±0.00 0.541±0.00 5.304±0.72 3.465±0.77 3.301±2.31 1.819±0.36 5.614±4.03 3.688±1.66 3.285±2.27 0.999±0.36 4.140±2.87 9.222±1.86 6.694±0.00
ENST00000460803 N/A N/A N/A N/A 1.621±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000473560 N/A N/A N/A N/A N/A 1.478±0.00 N/A N/A N/A 0.811±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005B4 CIL_0005B4_0002 CGP 1:43383917-43452650

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001104 IEA RNA polymerase II transcription cofactor activity
GO:0005515 IPI protein binding
GO:0005654 TAS nucleoplasm
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0010467 TAS gene expression
GO:0016567 IEA protein ubiquitination
GO:0016592 IDA:IEA mediator complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008064 med8 mediator complex subunit 8 protein_coding Danio_rerio
ENSDARG00000086596 MED8 (2 of 2) mediator complex subunit 8 protein_coding Danio_rerio
ENSMUSG00000006392 Med8 mediator complex subunit 8 protein_coding Mus_musculus

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