C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: natriuretic peptide receptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159899 NPR2 9606 + 9:35792154-35809732 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342694 NPR2-001 35792154-35809732 protein_coding
  ENST00000421267 NPR2-003 35805530-35808580 protein_coding
  ENST00000447210 NPR2-005 35806085-35809712 protein_coding
  ENST00000448821 NPR2-006 35806533-35809719 nonsense_mediated_decay
  ENST00000464810 NPR2-002 35792409-35809732 retained_intron
  ENST00000469249 NPR2-004 35808401-35809435 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342694ENST00000421267ENST00000447210ENST00000464810ENST00000469249
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342694 1.847±0.00 1.143±0.00 N/A 1.917±1.10 1.755±1.49 3.041±0.00 2.579±2.15 0.900±0.71 1.919±0.00 2.388±0.00 2.580±1.37 3.290±2.09 3.572±0.40 4.499±0.00
ENST00000421267 N/A 2.827±0.00 N/A N/A 1.065±0.00 N/A 0.836±0.00 N/A 1.605±0.00 N/A 3.961±0.00 N/A N/A N/A
ENST00000447210 N/A N/A N/A 1.642±0.00 N/A N/A N/A N/A N/A N/A 1.555±0.00 N/A N/A N/A
ENST00000464810 N/A 1.316±0.00 N/A N/A 2.346±0.00 0.180±0.00 N/A 0.230±0.00 N/A N/A N/A N/A N/A 4.722±0.00
ENST00000469249 5.626±0.00 4.620±0.00 1.522±0.00 4.757±1.15 3.705±1.62 N/A N/A 4.117±0.00 N/A 9.686±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007C4 CIL_0007C4_0001 CGP 9:35752990-35809732
CIL_0006IC CIL_0006IC_0001 CGP 9:35792154-35812272

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0004383 IDA guanylate cyclase activity
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004872 TAS receptor activity
GO:0004888 TAS transmembrane signaling receptor activity
GO:0005524 IEA ATP binding
GO:0005525 IEA GTP binding
GO:0005886 IEA plasma membrane
GO:0006182 IDA cGMP biosynthetic process
GO:0006468 IEA protein phosphorylation
GO:0007165 NAS signal transduction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007168 IDA receptor guanylyl cyclase signaling pathway
GO:0008217 TAS regulation of blood pressure
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0016941 IDA natriuretic peptide receptor activity
GO:0017046 IEA peptide hormone binding
GO:0035556 IEA intracellular signal transduction
GO:0042562 IPI hormone binding
GO:0042802 IEA identical protein binding
GO:0044702 IEA single organism reproductive process
GO:0051447 IEA negative regulation of meiotic cell cycle
GO:0060348 IEA bone development
GO:0097011 IEP cellular response to granulocyte macrophage colony-stimulating factor stimulus
GO:1900194 IEA negative regulation of oocyte maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011390 NPR2 natriuretic peptide receptor 2 protein_coding Danio_rerio
ENSMUSG00000028469 Npr2 natriuretic peptide receptor 2 protein_coding Mus_musculus

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