C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: natriuretic peptide receptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028469 Npr2 10090 + 4:43631935-43651244 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030191 Npr2-001 43631935-43651244 protein_coding
  ENSMUST00000107874 Npr2-002 43632185-43651244 protein_coding
  ENSMUST00000123351 Npr2-008 43641262-43644379 protein_coding
  ENSMUST00000123883 Npr2-003 43641116-43651244 processed_transcript
  ENSMUST00000128549 Npr2-004 43641284-43651244 protein_coding
  ENSMUST00000130093 Npr2-010 43646560-43650309 processed_transcript
  ENSMUST00000143160 Npr2-007 43647197-43648400 processed_transcript
  ENSMUST00000144418 Npr2-005 43641255-43643098 processed_transcript
  ENSMUST00000145817 Npr2-006 43644136-43648178 processed_transcript
  ENSMUST00000151603 Npr2-009 43648005-43650230 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030191ENSMUST00000107874ENSMUST00000123883ENSMUST00000128549
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030191 4.463±0.00 5.227±0.63 10.181±3.37 4.265±2.21 4.120±0.90 4.381±2.02 N/A N/A 0.691±0.83 11.557±3.06 8.893±3.26 14.213±4.62 1.475±0.56 0.572±0.17
ENSMUST00000107874 N/A N/A N/A 2.886±0.00 N/A N/A N/A N/A N/A N/A N/A 18.418±0.00 1.549±0.00 0.438±0.21
ENSMUST00000123883 8.501±1.35 N/A 4.390±0.00 4.531±1.50 N/A N/A 2.411±0.00 N/A 1.002±1.23 N/A N/A 6.819±0.00 0.523±0.10 0.264±0.00
ENSMUST00000128549 10.982±3.41 N/A 11.068±1.80 3.891±0.00 8.611±0.27 N/A 8.929±2.33 9.017±1.73 1.751±2.64 N/A 2.918±0.00 11.200±1.77 1.066±0.22 0.551±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007C4 CIL_0007C4_0002 CGP 4:43583216-43651244
CIL_0006IC CIL_0006IC_0002 CGP 4:43631935-43653594

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0004383 IDA guanylate cyclase activity
GO:0004672 IEA protein kinase activity
GO:0005524 IEA ATP binding
GO:0005525 IEA GTP binding
GO:0005886 TAS plasma membrane
GO:0006182 IDA cGMP biosynthetic process
GO:0006468 IEA protein phosphorylation
GO:0007168 IEA receptor guanylyl cyclase signaling pathway
GO:0016021 IEA integral component of membrane
GO:0016941 IDA natriuretic peptide receptor activity
GO:0017046 IEA peptide hormone binding
GO:0035556 IEA intracellular signal transduction
GO:0042562 IEA hormone binding
GO:0042802 IPI identical protein binding
GO:0044702 IMP single organism reproductive process
GO:0051447 IMP negative regulation of meiotic cell cycle
GO:0060348 IMP bone development
GO:0097011 IEA cellular response to granulocyte macrophage colony-stimulating factor stimulus
GO:1900194 IMP negative regulation of oocyte maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011390 NPR2 natriuretic peptide receptor 2 protein_coding Danio_rerio
ENSG00000159899 NPR2 natriuretic peptide receptor 2 protein_coding Homo_sapiens

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