C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: trefoil factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160181 TFF2 9606 - 21:42346357-42351128 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000291526 TFF2-001 42346357-42351128 protein_coding
  ENST00000463771 TFF2-003 42346374-42350997 processed_transcript
  ENST00000475297 TFF2-002 42346422-42350994 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastHeartKidneyLiverLungOvaryTestisENST00000291526ENST00000463771ENST00000475297
Transcript ID Adipose Adrenal Breast Heart Kidney Liver Lung Ovary Testis
ENST00000291526 N/A N/A 1.772±0.00 N/A N/A 0.532±0.00 N/A 0.591±0.00 N/A
ENST00000463771 0.629±0.00 N/A 0.890±0.71 N/A N/A N/A N/A 0.303±0.19 N/A
ENST00000475297 N/A 0.077±0.00 N/A 0.218±0.00 0.164±0.00 N/A 0.312±0.00 N/A 0.144±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QJ CIL_0008QJ_0001 VISTA 21:42290762-42894212
CIL_0004Y5 CIL_0004Y5_0001 CGP 21:42311667-42351128
CIL_00036E CIL_00036E_0001 CGP 21:42346357-42366594

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0007586 TAS digestion
GO:0008284 IEA positive regulation of cell proliferation
GO:0019722 IEA calcium-mediated signaling
GO:0030334 IEA regulation of cell migration
GO:0031723 IEA CXCR4 chemokine receptor binding
GO:0043031 IEA negative regulation of macrophage activation
GO:0050728 IEA negative regulation of inflammatory response
GO:0060455 IEA negative regulation of gastric acid secretion
GO:0070062 IDA extracellular vesicular exosome
GO:0070098 IEA chemokine-mediated signaling pathway
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000024028 Tff2 trefoil factor 2 (spasmolytic protein 1) protein_coding Mus_musculus

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