C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SIK family kinase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160584 SIK3 9606 - 11:116843402-117098437 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375300 SIK3-001 116843402-117098421 protein_coding
  ENST00000413553 SIK3-003 116868792-116957044 protein_coding
  ENST00000415541 SIK3-013 116845593-117098271 nonsense_mediated_decay
  ENST00000445177 SIK3-002 116843402-117098395 protein_coding
  ENST00000446921 SIK3-014 116845593-117098437 protein_coding
  ENST00000454905 SIK3-012 116845184-116849138 protein_coding
  ENST00000465421 SIK3-005 116845412-116865068 retained_intron
  ENST00000472648 SIK3-010 116874040-116875513 retained_intron
  ENST00000480222 SIK3-011 116867688-116873672 retained_intron
  ENST00000480468 SIK3-006 116856914-116861384 retained_intron
  ENST00000485363 SIK3-007 116904746-117098305 processed_transcript
  ENST00000488337 SIK3-004 116843402-116870251 processed_transcript
  ENST00000497049 SIK3-008 116893845-116957064 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000375300ENST00000413553ENST00000415541ENST00000445177ENST00000446921ENST00000465421ENST00000488337
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000375300 1.861±0.00 N/A N/A 5.371±2.98 N/A 1.019±0.25 3.485±0.00 N/A N/A N/A 2.936±1.66 1.304±0.09 N/A 4.436±0.00
ENST00000413553 N/A N/A N/A N/A N/A N/A N/A N/A 1.025±0.00 1.515±0.16 0.755±0.00 N/A N/A N/A
ENST00000415541 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.985±0.00 N/A N/A 19.863±12.74
ENST00000445177 1.661±0.00 1.825±0.00 1.043±0.00 2.013±0.00 1.921±0.43 N/A 0.746±0.00 4.777±0.00 1.331±0.57 1.630±0.86 N/A 4.075±1.23 4.558±1.34 11.218±0.00
ENST00000446921 2.205±0.00 2.119±0.00 N/A 6.546±0.00 2.079±0.00 2.147±0.00 1.786±0.93 2.523±0.00 1.404±0.16 2.432±0.00 7.228±0.00 2.756±1.41 2.054±0.09 10.870±1.23
ENST00000465421 N/A N/A N/A N/A N/A N/A N/A 1.447±0.00 N/A 2.336±0.00 0.691±0.00 N/A N/A N/A
ENST00000488337 1.982±0.00 N/A N/A 3.925±0.00 N/A N/A N/A 2.841±0.00 1.188±0.00 N/A N/A 1.917±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008EK CIL_0008EK_0001 VISTA 11:116351165-116951910
CIL_0007RC CIL_0007RC_0001 VISTA 11:116660805-117262910

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0001958 IEA endochondral ossification
GO:0004672 IEA protein kinase activity
GO:0004674 IEA:IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA:IDA ATP binding
GO:0005737 IEA cytoplasm
GO:0006468 IEA:IDA protein phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0032880 IEA regulation of protein localization
GO:0035108 IEA limb morphogenesis
GO:0035264 IEA multicellular organism growth
GO:0048705 IEA skeletal system morphogenesis
GO:0060351 IEA cartilage development involved in endochondral bone morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088083 SIK3 SIK family kinase 3 protein_coding Danio_rerio
ENSMUSG00000034135 Sik3 SIK family kinase 3 protein_coding Mus_musculus

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