C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenosine deaminase, RNA-specific
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160710 ADAR 9606 - 1:154582062-154627999 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368471 ADAR-002 154582067-154627964 protein_coding
  ENST00000368474 ADAR-001 154582062-154608206 protein_coding
  ENST00000463920 ADAR-003 154600177-154627986 retained_intron
  ENST00000471068 ADAR-005 154602096-154627999 processed_transcript
  ENST00000492630 ADAR-004 154584634-154585418 retained_intron
  ENST00000494866 ADAR-006 154602078-154627912 processed_transcript
  ENST00000526905 ADAR-008 154602199-154608812 processed_transcript
  ENST00000529168 ADAR-007 154584809-154602626 protein_coding
  ENST00000530954 ADAR-010 154585647-154588280 retained_intron
  ENST00000534279 ADAR-009 154585993-154588602 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368471ENST00000368474ENST00000529168
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368471 7.822±0.00 18.227±0.00 3.014±0.00 14.125±7.64 5.494±0.22 9.022±0.00 2.928±0.00 N/A 5.669±0.00 6.280±1.67 N/A 19.508±14.02 4.721±1.15 11.879±0.00
ENST00000368474 18.024±0.00 N/A 1.501±0.00 5.164±2.78 11.668±0.29 7.557±1.93 5.144±2.75 17.762±1.86 6.502±0.47 11.713±6.50 3.255±0.00 11.152±4.74 8.783±3.22 11.572±0.33
ENST00000529168 N/A N/A 3.383±0.00 N/A N/A N/A 1.015±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000LU CIL_0000LU_0002 CGP 1:154582062-154870280

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IEA osteoblast differentiation
GO:0001701 IEA in utero embryonic development
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0002566 IEA somatic diversification of immune receptors via somatic mutation
GO:0003677 IEA DNA binding
GO:0003723 IEA RNA binding
GO:0003726 NAS:IEA double-stranded RNA adenosine deaminase activity
GO:0004000 IEA adenosine deaminase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IEA nucleolus
GO:0005737 IDA cytoplasm
GO:0006382 IDA adenosine to inosine editing
GO:0006396 IEA RNA processing
GO:0006397 IEA mRNA processing
GO:0006606 IDA protein import into nucleus
GO:0006611 IDA protein export from nucleus
GO:0009615 IMP response to virus
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016553 IDA base conversion or substitution editing
GO:0016556 TAS mRNA modification
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030218 IEA erythrocyte differentiation
GO:0031054 IDA pre-miRNA processing
GO:0035196 IEA production of miRNAs involved in gene silencing by miRNA
GO:0035280 IDA miRNA loading onto RISC involved in gene silencing by miRNA
GO:0035455 IDA response to interferon-alpha
GO:0043066 IEA negative regulation of apoptotic process
GO:0044387 IMP negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0044530 IDA supraspliceosomal complex
GO:0044822 IDA poly(A) RNA binding
GO:0045070 IMP positive regulation of viral genome replication
GO:0045071 IEA negative regulation of viral genome replication
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0051607 IEA defense response to virus
GO:0060216 IEA definitive hemopoiesis
GO:0060337 TAS type I interferon signaling pathway
GO:0060339 IEA negative regulation of type I interferon-mediated signaling pathway
GO:0061484 IEA hematopoietic stem cell homeostasis
GO:1900369 IEA negative regulation of RNA interference

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012389 adar adenosine deaminase, RNA-specific protein_coding Danio_rerio
ENSMUSG00000027951 Adar adenosine deaminase, RNA-specific protein_coding Mus_musculus

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