C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenosine deaminase, RNA-specific
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027951 Adar 10090 + 3:89715022-89753446 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029563 Adar-002 89730748-89751406 protein_coding
  ENSMUST00000098924 Adar-005 89715022-89753446 protein_coding
  ENSMUST00000107405 Adar-001 89730748-89753446 protein_coding
  ENSMUST00000118341 Adar-004 89730748-89751406 protein_coding
  ENSMUST00000121094 Adar-003 89730748-89751406 protein_coding
  ENSMUST00000123691 Adar-006 89715332-89735153 processed_transcript
  ENSMUST00000131030 Adar-008 89745645-89747211 retained_intron
  ENSMUST00000150637 Adar-007 89737586-89739289 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029563ENSMUST00000098924ENSMUST00000107405ENSMUST00000118341ENSMUST00000121094ENSMUST00000131030
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029563 N/A N/A N/A N/A N/A N/A N/A 1.441±0.00 N/A N/A 0.262±0.10 6.519±1.31 2.639±2.15 N/A
ENSMUST00000098924 3.023±0.00 2.040±0.52 2.849±0.52 19.111±4.39 N/A 2.157±0.26 0.801±0.14 0.948±0.00 0.940±0.05 1.639±0.00 0.251±0.00 2.519±0.59 0.491±0.00 0.838±0.48
ENSMUST00000107405 6.543±3.50 4.321±1.49 6.216±0.07 N/A 4.713±2.21 5.604±3.54 1.384±0.46 2.442±1.23 3.469±2.43 5.680±3.05 0.372±0.15 4.089±1.99 1.899±0.25 0.508±0.34
ENSMUST00000118341 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.464±0.13 N/A N/A N/A
ENSMUST00000121094 N/A N/A N/A N/A N/A N/A N/A N/A 2.948±1.04 N/A N/A N/A N/A N/A
ENSMUST00000131030 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.382±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IMP osteoblast differentiation
GO:0001701 IMP in utero embryonic development
GO:0002244 IMP hematopoietic progenitor cell differentiation
GO:0002566 IDA somatic diversification of immune receptors via somatic mutation
GO:0003692 TAS left-handed Z-DNA binding
GO:0003726 IDA double-stranded RNA adenosine deaminase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006382 IMP adenosine to inosine editing
GO:0006397 IEA mRNA processing
GO:0006606 IEA protein import into nucleus
GO:0006611 IEA protein export from nucleus
GO:0009615 ISS response to virus
GO:0016020 IEA membrane
GO:0016553 IEA base conversion or substitution editing
GO:0030218 IMP erythrocyte differentiation
GO:0031054 IEA pre-miRNA processing
GO:0035196 IMP production of miRNAs involved in gene silencing by miRNA
GO:0035280 ISO miRNA loading onto RISC involved in gene silencing by miRNA
GO:0035455 ISS response to interferon-alpha
GO:0043066 IMP negative regulation of apoptotic process
GO:0044387 IMP negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0044530 ISS supraspliceosomal complex
GO:0044822 IEA poly(A) RNA binding
GO:0045070 IMP positive regulation of viral genome replication
GO:0045071 IMP negative regulation of viral genome replication
GO:0045087 IEA innate immune response
GO:0046872 IEA metal ion binding
GO:0051607 IMP defense response to virus
GO:0060216 IMP definitive hemopoiesis
GO:0060339 IMP negative regulation of type I interferon-mediated signaling pathway
GO:0061484 IMP hematopoietic stem cell homeostasis
GO:1900369 IMP negative regulation of RNA interference

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012389 adar adenosine deaminase, RNA-specific protein_coding Danio_rerio
ENSG00000160710 ADAR adenosine deaminase, RNA-specific protein_coding Homo_sapiens

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