C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hypocretin (orexin) neuropeptide precursor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000161610 HCRT 9606 - 17:42184060-42185452 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000293330 HCRT-001 42184060-42185452 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LungTestisENST00000293330
Transcript ID Lung Testis
ENST00000293330 0.468±0.00 0.387±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002J4 CIL_0002J4_0001 CGP 17:42156891-42185452
CIL_0006DQ CIL_0006DQ_0001 CGP 17:42184060-42194532

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005576 TAS extracellular region
GO:0005737 IEA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007218 IEA neuropeptide signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007631 IEA feeding behavior
GO:0008021 TAS synaptic vesicle
GO:0008156 IEA negative regulation of DNA replication
GO:0030054 IEA cell junction
GO:0030141 IEA secretory granule
GO:0031771 IEA type 1 hypocretin receptor binding
GO:0031772 IEA type 2 hypocretin receptor binding
GO:0042755 IEA eating behavior
GO:0043267 IEA negative regulation of potassium ion transport
GO:0046928 IEA regulation of neurotransmitter secretion
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051928 IEA positive regulation of calcium ion transport
GO:0051970 IEA negative regulation of transmission of nerve impulse
GO:0051971 IEA positive regulation of transmission of nerve impulse
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070932 hcrt hypocretin (orexin) neuropeptide precursor protein_coding Danio_rerio
ENSMUSG00000045471 Hcrt hypocretin protein_coding Mus_musculus

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