C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hypocretin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045471 Hcrt 10090 - 11:100761069-100762931 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055083 Hcrt-001 100761691-100762931 protein_coding
  ENSMUST00000107360 Hcrt-002 100761069-100762928 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverOvaryPlacentaTestisENSMUST00000055083ENSMUST00000107360
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Ovary Placenta Testis
ENSMUST00000055083 0.110±0.00 N/A 0.072±0.00 3.930±5.12 N/A 0.172±0.10 0.201±0.02 0.043±0.02 0.253±0.07 0.196±0.00 0.996±0.34
ENSMUST00000107360 N/A 0.224±0.14 N/A N/A 0.154±0.01 N/A N/A N/A N/A 0.016±0.00 1.057±0.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002J4 CIL_0002J4_0002 CGP 11:100740376-100762931
CIL_0006DQ CIL_0006DQ_0002 CGP 11:100761069-100770957

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005737 IEA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007218 IEA neuropeptide signaling pathway
GO:0007631 IEA feeding behavior
GO:0008156 IEA negative regulation of DNA replication
GO:0030054 IEA cell junction
GO:0030141 IEA secretory granule
GO:0031771 IEA type 1 hypocretin receptor binding
GO:0031772 IEA type 2 hypocretin receptor binding
GO:0042755 IEA eating behavior
GO:0043267 IEA negative regulation of potassium ion transport
GO:0045202 IEA synapse
GO:0046928 IEA regulation of neurotransmitter secretion
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051928 IEA positive regulation of calcium ion transport
GO:0051970 IEA negative regulation of transmission of nerve impulse
GO:0051971 IEA positive regulation of transmission of nerve impulse
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070932 hcrt hypocretin (orexin) neuropeptide precursor protein_coding Danio_rerio
ENSG00000161610 HCRT hypocretin (orexin) neuropeptide precursor protein_coding Homo_sapiens

Loading