C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 23 receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162594 IL23R 9606 + 1:67166400-67259979 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000347310 IL23R-001 67166400-67259979 protein_coding
  ENST00000395227 IL23R-201 67219557-67259671 protein_coding
  ENST00000425614 IL23R-003 67207616-67259248 protein_coding
  ENST00000473881 IL23R-002 67207638-67259675 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryTestisENST00000347310ENST00000395227ENST00000425614
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Testis
ENST00000347310 0.036±0.00 0.061±0.00 0.018±0.00 0.007±0.00 0.643±0.00 0.013±0.00 0.029±0.01 0.015±0.00 0.098±0.02 0.046±0.04 0.136±0.04
ENST00000395227 N/A N/A N/A N/A N/A 0.016±0.00 N/A N/A N/A 0.072±0.06 N/A
ENST00000425614 N/A N/A N/A N/A N/A N/A 0.046±0.00 N/A N/A 0.088±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00069F CIL_00069F_0001 CGP 1:66999332-67231853

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001916 ISS positive regulation of T cell mediated cytotoxicity
GO:0002230 ISS positive regulation of defense response to virus by host
GO:0002827 ISS positive regulation of T-helper 1 type immune response
GO:0005143 IPI interleukin-12 receptor binding
GO:0005515 IEA protein binding
GO:0006954 IEA inflammatory response
GO:0010535 IC positive regulation of activation of JAK2 kinase activity
GO:0032496 IDA response to lipopolysaccharide
GO:0032693 IMP negative regulation of interleukin-10 production
GO:0032725 IC positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032729 IDA positive regulation of interferon-gamma production
GO:0032735 IDA positive regulation of interleukin-12 production
GO:0032740 IC positive regulation of interleukin-17 production
GO:0032819 IC positive regulation of natural killer cell proliferation
GO:0034341 IDA response to interferon-gamma
GO:0038155 IDA interleukin-23-mediated signaling pathway
GO:0042019 IPI interleukin-23 binding
GO:0042020 IDA interleukin-23 receptor activity
GO:0042102 IC positive regulation of T cell proliferation
GO:0042104 IC positive regulation of activated T cell proliferation
GO:0042510 IC regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517 IC positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042520 IC positive regulation of tyrosine phosphorylation of Stat4 protein
GO:0042523 IC positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0043235 IDA receptor complex
GO:0043382 ISS positive regulation of memory T cell differentiation
GO:0045672 IC positive regulation of osteoclast differentiation
GO:0050829 IC defense response to Gram-negative bacterium
GO:0051135 IC positive regulation of NK T cell activation
GO:0072536 IDA interleukin-23 receptor complex
GO:2000318 ISS positive regulation of T-helper 17 type immune response
GO:2000330 ISS positive regulation of T-helper 17 cell lineage commitment

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000049093 Il23r interleukin 23 receptor protein_coding Mus_musculus

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