C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interleukin 23 receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000395227 IL23R-201 ENSG00000162594 9606 + 1:67219557-67259671 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartOvaryENST00000395227
Transcript ID Heart Ovary
ENST00000395227 0.016±0.00 0.072±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00069F CIL_00069F_0001 CGP 1:66999332-67231853

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001916 ISS positive regulation of T cell mediated cytotoxicity
GO:0002230 ISS positive regulation of defense response to virus by host
GO:0002827 ISS positive regulation of T-helper 1 type immune response
GO:0005143 IPI interleukin-12 receptor binding
GO:0006954 IEA inflammatory response
GO:0010535 IC positive regulation of activation of JAK2 kinase activity
GO:0032496 IDA response to lipopolysaccharide
GO:0032693 IMP negative regulation of interleukin-10 production
GO:0032725 IC positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032729 IDA positive regulation of interferon-gamma production
GO:0032735 IDA positive regulation of interleukin-12 production
GO:0032740 IC positive regulation of interleukin-17 production
GO:0032819 IC positive regulation of natural killer cell proliferation
GO:0034341 IDA response to interferon-gamma
GO:0038155 IDA interleukin-23-mediated signaling pathway
GO:0042019 IPI interleukin-23 binding
GO:0042020 IDA interleukin-23 receptor activity
GO:0042102 IC positive regulation of T cell proliferation
GO:0042104 IC positive regulation of activated T cell proliferation
GO:0042510 IC regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517 IC positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042520 IC positive regulation of tyrosine phosphorylation of Stat4 protein
GO:0042523 IC positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0043235 IDA receptor complex
GO:0043382 ISS positive regulation of memory T cell differentiation
GO:0045672 IC positive regulation of osteoclast differentiation
GO:0050829 IC defense response to Gram-negative bacterium
GO:0051135 IC positive regulation of NK T cell activation
GO:0072536 IDA interleukin-23 receptor complex
GO:2000318 ISS positive regulation of T-helper 17 type immune response
GO:2000330 ISS positive regulation of T-helper 17 cell lineage commitment

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000118364 Il23r-001 protein_coding Mus_musculus 0 405

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