C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nexilin (F actin binding protein)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162614 NEXN 9606 + 1:77888513-77943895 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330010 NEXN-201 77888515-77943891 protein_coding
  ENST00000334785 NEXN-001 77888628-77943224 protein_coding
  ENST00000342754 NEXN-005 77918128-77943895 protein_coding
  ENST00000401035 NEXN-002 77888513-77933384 protein_coding
  ENST00000440324 NEXN-003 77888662-77935919 protein_coding
  ENST00000464998 NEXN-007 77926569-77935970 retained_intron
  ENST00000470735 NEXN-006 77941711-77942753 retained_intron
  ENST00000480732 NEXN-004 77931662-77943199 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330010ENST00000334785ENST00000342754ENST00000401035ENST00000440324ENST00000480732
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330010 N/A N/A N/A 0.212±0.17 1.904±0.00 3.138±2.72 1.548±0.00 1.214±0.00 2.937±0.00 1.355±1.02 N/A 3.715±0.68 4.086±2.61 2.973±0.00
ENST00000334785 2.690±0.00 6.208±0.00 0.112±0.00 N/A 2.609±0.00 N/A 32.922±31.89 1.085±0.00 0.513±0.16 N/A 0.743±0.00 1.183±0.00 N/A 3.050±0.00
ENST00000342754 5.024±0.00 9.399±0.00 N/A 0.764±0.00 8.169±0.00 21.369±0.00 37.990±37.42 5.313±0.00 0.634±0.00 1.242±0.79 47.094±45.30 2.046±0.17 1.363±0.94 18.005±0.00
ENST00000401035 N/A N/A 0.174±0.00 0.060±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000440324 N/A N/A N/A 0.594±0.00 N/A 0.448±0.00 0.980±0.00 0.114±0.00 N/A N/A N/A 1.504±0.00 3.868±0.00 2.400±0.00
ENST00000480732 N/A N/A N/A N/A N/A N/A 1.385±0.00 N/A 1.707±0.00 N/A N/A 0.122±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YZ CIL_0008YZ_0001 VISTA 1:77533579-78136618
CIL_0007KB CIL_0007KB_0001 UCNEbase 1:77564480-77948632

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004683 IBA calmodulin-dependent protein kinase activity
GO:0005515 IEA protein binding
GO:0005856 IEA cytoskeleton
GO:0005924 IEA cell-substrate adherens junction
GO:0005925 IDA focal adhesion
GO:0006468 IBA protein phosphorylation
GO:0008307 IMP structural constituent of muscle
GO:0030018 ISS Z disc
GO:0030334 IDA regulation of cell migration
GO:0048739 IBA cardiac muscle fiber development
GO:0051015 IDA actin filament binding
GO:0051493 IEP regulation of cytoskeleton organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057317 nexn nexilin (F actin binding protein) protein_coding Danio_rerio
ENSMUSG00000039103 Nexn nexilin protein_coding Mus_musculus

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