C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanylate binding protein 2, interferon-inducible
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162645 GBP2 9606 - 1:89106132-89150456 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370466 GBP2-002 89108000-89126114 protein_coding
  ENST00000463660 GBP2-003 89110187-89120220 processed_transcript
  ENST00000464839 GBP2-001 89106132-89150456 nonsense_mediated_decay
  ENST00000493802 GBP2-004 89108117-89113050 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370466ENST00000463660ENST00000464839ENST00000493802
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370466 49.648±0.00 22.980±0.00 N/A 2.041±1.71 22.394±9.04 32.406±28.85 2.818±1.58 14.193±0.00 13.952±2.16 69.591±60.79 37.374±0.00 27.855±19.42 14.266±3.73 11.620±5.72
ENST00000463660 N/A N/A 0.402±0.00 0.161±0.00 N/A 1.024±0.00 0.332±0.00 N/A N/A 3.929±0.00 0.209±0.00 1.425±0.00 N/A N/A
ENST00000464839 N/A N/A N/A N/A N/A 0.848±0.00 0.164±0.00 0.964±0.00 1.589±0.00 6.068±4.70 N/A 2.624±0.00 N/A 1.405±0.00
ENST00000493802 N/A N/A N/A 0.680±0.00 13.609±0.00 37.744±0.00 N/A 6.870±0.00 N/A N/A N/A N/A N/A 8.743±2.87

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000033 CIL_000033_0004 CGP 1:89052319-89150456
CIL_000033 CIL_000033_0006 CGP 1:89106132-89176040

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005634 IEA nucleus
GO:0005794 IEA Golgi apparatus
GO:0005829 TAS cytosol
GO:0006184 IEA GTP catabolic process
GO:0006955 TAS immune response
GO:0016020 IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0020005 IEA symbiont-containing vacuole membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0035458 IEA cellular response to interferon-beta
GO:0042832 IEA defense response to protozoan
GO:0044406 IEA adhesion of symbiont to host
GO:0050830 IEA defense response to Gram-positive bacterium
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071346 IEA cellular response to interferon-gamma

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005627 CABZ01068209.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000034063 CABZ01068208.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000038668 gbp1 guanylate binding protein 1 protein_coding Danio_rerio
ENSDARG00000038669 gbp2 guanylate binding protein 2 protein_coding Danio_rerio
ENSDARG00000067663 si:ch211-209n20.1 si:ch211-209n20.1 protein_coding Danio_rerio
ENSDARG00000068857 gbp4 guanylate binding protein 4 protein_coding Danio_rerio
ENSDARG00000074988 si:ch211-209n20.1 si:ch211-209n20.1 protein_coding Danio_rerio
ENSMUSG00000028270 Gbp2 guanylate binding protein 2 protein_coding Mus_musculus

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