C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: guanylate binding protein 2, interferon-inducible
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000370466 GBP2-002 ENSG00000162645 9606 - 1:89108000-89126114 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370466
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370466 49.648±0.00 22.980±0.00 2.041±1.71 22.394±9.04 32.406±28.85 2.818±1.58 14.193±0.00 13.952±2.16 69.591±60.79 37.374±0.00 27.855±19.42 14.266±3.73 11.620±5.72

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000033 CIL_000033_0004 CGP 1:89052319-89150456
CIL_000033 CIL_000033_0006 CGP 1:89106132-89176040

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005634 IEA nucleus
GO:0005794 IEA Golgi apparatus
GO:0005829 TAS cytosol
GO:0006184 IEA GTP catabolic process
GO:0006955 TAS immune response
GO:0016020 IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0020005 IEA symbiont-containing vacuole membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0035458 IEA cellular response to interferon-beta
GO:0042832 IEA defense response to protozoan
GO:0044406 IEA adhesion of symbiont to host
GO:0050830 IEA defense response to Gram-positive bacterium
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071346 IEA cellular response to interferon-gamma

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029936 Gbp5-001 protein_coding Mus_musculus 0 1219
ENSMUST00000165774 Gbp2-001 protein_coding Mus_musculus 0 1171
ENSMUST00000090127 Gbp5-201 protein_coding Mus_musculus 0 542
ENSMUST00000169572 Gbp2-002 nonsense_mediated_decay Mus_musculus 0 329

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