C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: activating transcription factor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162772 ATF3 9606 + 1:212565334-212620777 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336937 ATF3-006 212615022-212619266 protein_coding
  ENST00000341491 ATF3-001 212608670-212620777 protein_coding
  ENST00000366981 ATF3-002 212565334-212619535 protein_coding
  ENST00000366983 ATF3-004 212615022-212619555 protein_coding
  ENST00000366985 ATF3-007 212608915-212619611 protein_coding
  ENST00000366987 ATF3-201 212565334-212620772 protein_coding
  ENST00000464547 ATF3-003 212615022-212619555 nonsense_mediated_decay
  ENST00000465155 ATF3-005 212608670-212619247 retained_intron
  ENST00000492118 ATF3-008 212613436-212620777 processed_transcript
  ENST00000613104 ATF3-009 212615178-212619746 protein_coding
  ENST00000613954 ATF3-202 212608628-212620772 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000341491ENST00000366985ENST00000366987ENST00000464547ENST00000465155ENST00000492118ENST00000613104ENST00000613954
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000341491 14.070±0.00 6.366±0.00 6.475±0.00 12.600±8.64 18.178±0.00 21.806±0.00 2.903±2.69 5.894±0.00 108.585±0.00 6.815±0.00 28.538±22.34 39.179±17.33 7.474±6.64
ENST00000366985 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.857±0.00
ENST00000366987 N/A N/A 1.024±0.00 N/A N/A N/A 0.180±0.00 N/A N/A N/A N/A N/A N/A
ENST00000464547 N/A N/A 0.707±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000465155 N/A N/A N/A N/A N/A N/A N/A 2.669±0.00 3.196±0.00 N/A N/A N/A 0.415±0.00
ENST00000492118 N/A N/A 0.208±0.00 N/A N/A N/A 0.367±0.00 N/A N/A 1.227±0.00 N/A N/A N/A
ENST00000613104 13.695±0.00 9.190±0.00 12.077±0.00 N/A 16.066±0.00 18.572±0.00 N/A N/A N/A 5.938±0.00 21.837±0.00 26.863±0.00 N/A
ENST00000613954 N/A N/A N/A 3.004±0.00 N/A 0.769±0.00 N/A N/A N/A 5.377±0.00 6.592±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008JQ CIL_0008JQ_0001 VISTA 1:212231404-212833951

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001228 IC RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IEA DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0006094 IEA gluconeogenesis
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0008284 IEA positive regulation of cell proliferation
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0035914 IEA skeletal muscle cell differentiation
GO:0042802 IPI identical protein binding
GO:0043565 IEA sequence-specific DNA binding
GO:0044267 TAS cellular protein metabolic process
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007823 atf3 activating transcription factor 3 protein_coding Danio_rerio
ENSMUSG00000026628 Atf3 activating transcription factor 3 protein_coding Mus_musculus

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