C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: activating transcription factor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026628 Atf3 10090 - 1:191170296-191183340 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027941 Atf3-001 191170296-191183340 protein_coding
  ENSMUST00000131854 Atf3-002 191171425-191183108 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027941ENSMUST00000131854
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027941 2.980±0.43 1.579±0.70 3.235±1.34 0.341±0.16 4.146±0.64 14.677±3.67 2.102±0.26 0.722±0.12 0.671±0.35 4.261±1.64 1.341±0.49 3.829±1.18 17.447±12.48 0.078±0.05
ENSMUST00000131854 N/A N/A N/A 0.460±0.00 N/A N/A N/A N/A N/A N/A N/A 8.118±0.00 55.077±32.99 0.132±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008JQ CIL_0008JQ_0002 VISTA 1:190939014-191541717

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IDA DNA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IEA nucleolus
GO:0006094 IDA gluconeogenesis
GO:0006351 IEA transcription, DNA-templated
GO:0008284 IEA positive regulation of cell proliferation
GO:0035914 IMP skeletal muscle cell differentiation
GO:0042802 IEA identical protein binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007823 atf3 activating transcription factor 3 protein_coding Danio_rerio
ENSG00000162772 ATF3 activating transcription factor 3 protein_coding Homo_sapiens

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