C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nitric oxide synthase trafficking
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163072 NOSTRIN 9606 + 2:168786539-168865514 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317647 NOSTRIN-001 168802418-168865514 protein_coding
  ENST00000397206 NOSTRIN-012 168802636-168864970 protein_coding
  ENST00000397209 NOSTRIN-004 168802647-168864970 protein_coding
  ENST00000427068 NOSTRIN-008 168855422-168859533 nonsense_mediated_decay
  ENST00000439509 NOSTRIN-011 168802592-168831533 nonsense_mediated_decay
  ENST00000444448 NOSTRIN-201 168798151-168865339 protein_coding
  ENST00000445023 NOSTRIN-003 168802597-168865054 protein_coding
  ENST00000447264 NOSTRIN-007 168811334-168851182 protein_coding
  ENST00000458381 NOSTRIN-002 168786539-168865055 protein_coding
  ENST00000471833 NOSTRIN-006 168802639-168812084 retained_intron
  ENST00000472260 NOSTRIN-005 168855686-168865054 retained_intron
  ENST00000486873 NOSTRIN-010 168843052-168855654 retained_intron
  ENST00000495202 NOSTRIN-009 168859109-168860838 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000317647ENST00000397206ENST00000397209ENST00000445023ENST00000447264ENST00000472260ENST00000486873
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000317647 N/A N/A 1.010±0.00 N/A N/A 2.146±0.00 0.514±0.00 N/A 0.285±0.00 2.362±0.00 N/A 1.363±0.73 2.602±0.00 2.807±0.00
ENST00000397206 2.639±0.00 N/A 1.252±0.00 1.274±0.49 N/A 2.228±0.00 N/A 3.031±0.00 N/A 6.194±0.82 1.303±0.00 2.271±0.68 N/A N/A
ENST00000397209 7.665±0.00 5.135±0.00 N/A N/A 4.702±2.56 2.706±0.00 1.559±0.74 2.521±1.93 0.905±0.02 5.024±0.94 N/A 1.194±0.00 N/A 8.175±0.00
ENST00000445023 4.026±0.00 3.387±0.00 N/A 0.802±0.00 3.697±1.95 4.389±0.00 3.846±0.00 5.947±0.00 2.226±0.00 9.092±0.00 N/A 2.371±0.55 6.803±2.42 5.243±1.29
ENST00000447264 N/A N/A 1.851±0.00 N/A 5.018±0.00 2.029±0.00 0.707±0.00 0.979±0.00 1.242±0.00 N/A N/A 2.581±0.00 6.447±0.00 N/A
ENST00000472260 N/A 2.155±0.00 N/A N/A 3.897±0.00 1.385±0.04 N/A N/A 0.564±0.00 N/A N/A 2.419±1.24 N/A 4.312±0.00
ENST00000486873 N/A N/A N/A N/A N/A N/A N/A N/A 1.310±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00063C CIL_00063C_0001 CGP 2:168455862-168865514
CIL_000639 CIL_000639_0001 CGP 2:168786539-168913371

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005856 IEA cytoskeleton
GO:0005886 TAS plasma membrane
GO:0006897 IEA endocytosis
GO:0007165 IEA signal transduction
GO:0030666 TAS endocytic vesicle membrane
GO:0044281 TAS small molecule metabolic process
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046209 TAS nitric oxide metabolic process
GO:0050999 IEA:TAS regulation of nitric-oxide synthase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077866 nostrin nitric oxide synthase trafficker protein_coding Danio_rerio
ENSMUSG00000034738 Nostrin nitric oxide synthase trafficker protein_coding Mus_musculus

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