C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prokineticin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163421 PROK2 9606 - 3:71771656-71785206 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295619 PROK2-002 71772101-71785061 protein_coding
  ENST00000353065 PROK2-001 71771656-71785206 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295619ENST00000353065
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295619 N/A N/A 0.154±0.00 N/A N/A 0.044±0.00 N/A N/A N/A 0.079±0.00 0.033±0.02 0.373±0.00 4.334±0.00
ENST00000353065 0.413±0.00 0.079±0.00 0.090±0.00 0.056±0.02 0.168±0.00 0.150±0.00 0.035±0.00 0.195±0.00 3.246±2.85 N/A 0.042±0.02 0.605±0.04 2.369±0.63

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008EM CIL_0008EM_0001 VISTA 3:71224456-71825389
CIL_0007YY CIL_0007YY_0001 VISTA 3:71241746-71843635
CIL_00088J CIL_00088J_0001 VISTA 3:71639690-72241632
CIL_0001TB CIL_0001TB_0002 CGP 3:71754050-71785206
CIL_0003N4 CIL_0003N4_0002 CGP 3:71771656-72446918

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 TAS activation of MAPK activity
GO:0001525 IDA angiogenesis
GO:0001664 TAS G-protein coupled receptor binding
GO:0005576 TAS extracellular region
GO:0006935 IDA chemotaxis
GO:0006954 NAS inflammatory response
GO:0007186 NAS G-protein coupled receptor signaling pathway
GO:0007204 TAS positive regulation of cytosolic calcium ion concentration
GO:0007218 IEA neuropeptide signaling pathway
GO:0007283 IMP spermatogenesis
GO:0007623 IEA circadian rhythm
GO:0008283 IDA cell proliferation
GO:0019233 TAS sensory perception of pain
GO:0043066 IDA negative regulation of apoptotic process
GO:0045987 IDA positive regulation of smooth muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091616 prok2 prokineticin 2 protein_coding Danio_rerio
ENSMUSG00000030069 Prok2 prokineticin 2 protein_coding Mus_musculus

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