C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163464 CXCR1 9606 - 2:218162845-218166995 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295683 CXCR1-001 218162845-218166995 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295683
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295683 2.262±0.00 0.222±0.00 0.095±0.02 0.143±0.00 0.615±0.00 0.137±0.08 0.111±0.07 0.303±0.22 8.773±6.15 0.347±0.00 0.230±0.15 2.292±0.87 0.418±0.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WL CIL_0007WL_0001 VISTA 2:217636448-218238840
CIL_0005VN CIL_0005VN_0001 CGP 2:218125289-218166995
CIL_0005VM CIL_0005VM_0001 CGP 2:218162845-218254356

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002407 TAS dendritic cell chemotaxis
GO:0004918 IDA interleukin-8 receptor activity
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0004950 TAS chemokine receptor activity
GO:0005886 TAS plasma membrane
GO:0006935 TAS chemotaxis
GO:0006954 TAS inflammatory response
GO:0007166 IDA cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0019959 IPI interleukin-8 binding
GO:0031623 IDA receptor internalization
GO:0038112 IDA interleukin-8-mediated signaling pathway
GO:0070098 IEA chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054975 CXCR1 chemokine (C-X-C motif) receptor 1 protein_coding Danio_rerio
ENSMUSG00000048480 Cxcr1 chemokine (C-X-C motif) receptor 1 protein_coding Mus_musculus

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