C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000048480 Cxcr1 10090 - 1:74191785-74194631 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000053389 Cxcr1-001 74191785-74194631 protein_coding
  ENSMUST00000190313 Cxcr1-002 74191785-74193235 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000053389ENSMUST00000190313
Transcript ID Bladder Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000053389 0.031±0.00 0.007±0.00 0.152±0.13 0.026±0.00 0.030±0.00 0.021±0.01 0.292±0.03 0.062±0.02 0.576±0.26 0.029±0.01
ENSMUST00000190313 0.052±0.00 N/A N/A N/A N/A 0.029±0.00 N/A N/A 0.108±0.03 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WL CIL_0007WL_0002 VISTA 1:73730234-74332407
CIL_0005VN CIL_0005VN_0002 CGP 1:74153989-74194631
CIL_0005VM CIL_0005VM_0002 CGP 1:74191785-74268209

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004918 IEA interleukin-8 receptor activity
GO:0005886 IEA plasma membrane
GO:0006935 IEA chemotaxis
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0016021 IEA integral component of membrane
GO:0016494 IEA C-X-C chemokine receptor activity
GO:0019959 IEA interleukin-8 binding
GO:0031623 IEA receptor internalization
GO:0038112 IEA interleukin-8-mediated signaling pathway
GO:0070098 IEA chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054975 CXCR1 chemokine (C-X-C motif) receptor 1 protein_coding Danio_rerio
ENSG00000163464 CXCR1 chemokine (C-X-C motif) receptor 1 protein_coding Homo_sapiens

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