C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade I (neuroserpin), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163536 SERPINI1 9606 + 3:167735243-167825568 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295777 SERPINI1-001 167735723-167825566 protein_coding
  ENST00000446050 SERPINI1-002 167735430-167825568 protein_coding
  ENST00000466865 SERPINI1-013 167807238-167825560 protein_coding
  ENST00000472747 SERPINI1-007 167735725-167794679 protein_coding
  ENST00000472941 SERPINI1-003 167735243-167790602 protein_coding
  ENST00000488374 SERPINI1-012 167800046-167825562 processed_transcript
  ENST00000494666 SERPINI1-009 167822936-167825560 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295777ENST00000446050ENST00000466865ENST00000472747ENST00000472941ENST00000494666
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295777 0.158±0.00 N/A 0.495±0.00 20.847±4.93 N/A N/A 0.178±0.06 N/A 0.054±0.00 0.813±0.00 N/A 0.557±0.19 0.163±0.01 0.872±0.00
ENST00000446050 0.223±0.00 1.758±0.00 0.166±0.00 25.816±3.98 2.162±0.61 0.724±0.00 0.293±0.20 0.684±0.00 0.025±0.00 N/A N/A 1.215±0.48 0.381±0.11 2.675±0.47
ENST00000466865 N/A N/A 0.823±0.00 N/A 0.967±0.00 N/A N/A 1.352±0.00 N/A N/A N/A 1.627±0.00 1.100±0.59 N/A
ENST00000472747 N/A N/A N/A N/A N/A N/A N/A 0.131±0.00 N/A N/A N/A N/A N/A N/A
ENST00000472941 N/A N/A N/A N/A N/A N/A N/A N/A 0.102±0.00 N/A 1.402±0.00 N/A N/A N/A
ENST00000494666 N/A N/A N/A N/A N/A N/A N/A N/A 0.186±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00049O CIL_00049O_0002 CGP 3:167683298-167825568

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005615 IEA extracellular space
GO:0007417 TAS central nervous system development
GO:0007422 TAS peripheral nervous system development
GO:0008219 IEA cell death
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030155 IEA regulation of cell adhesion
GO:0030162 IBA regulation of proteolysis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034168 serpini1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 protein_coding Danio_rerio
ENSMUSG00000027834 Serpini1 serine (or cysteine) peptidase inhibitor, clade I, member 1 protein_coding Mus_musculus

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