C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine (or cysteine) peptidase inhibitor, clade I, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027834 Serpini1 10090 + 3:75557547-75643495 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029423 Serpini1-001 75557547-75643495 protein_coding
  ENSMUST00000161695 Serpini1-003 75557578-75616201 retained_intron
  ENSMUST00000161776 Serpini1-002 75557547-75616709 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029423ENSMUST00000161695ENSMUST00000161776
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029423 0.439±0.31 0.315±0.08 0.881±0.01 21.111±2.17 0.325±0.16 0.270±0.14 0.807±0.16 0.597±0.13 0.129±0.07 0.123±0.04 0.225±0.08 0.999±0.56 0.282±0.13 0.683±0.27
ENSMUST00000161695 N/A N/A N/A N/A N/A N/A N/A N/A 0.077±0.00 N/A N/A 0.897±0.25 N/A N/A
ENSMUST00000161776 3.334±2.00 0.668±0.25 1.349±0.25 N/A 1.917±0.37 1.367±0.44 4.568±2.23 4.258±1.10 0.176±0.08 0.379±0.17 0.310±0.02 13.597±2.31 0.317±0.03 4.175±0.95

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00049O CIL_00049O_0003 CGP 3:75516490-75643495

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005615 IEA extracellular space
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030155 IEA regulation of cell adhesion
GO:0030162 IBA regulation of proteolysis
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034168 serpini1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 protein_coding Danio_rerio
ENSG00000163536 SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 protein_coding Homo_sapiens

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