C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: F-box protein 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164117 FBXO8 9606 - 4:174236658-174284264 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000393674 FBXO8-001 174236658-174284264 protein_coding
  ENST00000503293 FBXO8-002 174236969-174283667 protein_coding
  ENST00000513696 FBXO8-004 174241123-174283663 protein_coding
  ENST00000515664 FBXO8-003 174237359-174283646 nonsense_mediated_decay
  ENST00000615392 FBXO8-201 174236658-174263092 protein_coding
  ENST00000620592 FBXO8-202 174236658-174284251 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000503293ENST00000513696ENST00000515664ENST00000615392ENST00000620592
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000503293 4.557±0.00 2.888±0.00 2.755±0.00 2.090±0.14 4.787±0.40 6.486±0.00 6.060±0.00 4.802±0.12 5.281±0.00 3.785±0.20 N/A 4.058±1.53 6.708±1.76 6.796±0.00
ENST00000513696 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.594±0.00 N/A N/A
ENST00000515664 4.863±0.00 2.796±0.00 1.631±0.00 1.946±0.61 5.836±0.00 4.466±2.05 3.613±1.44 7.586±0.00 3.061±0.00 4.126±0.00 1.265±0.00 1.695±0.00 4.800±1.69 6.752±0.00
ENST00000615392 N/A N/A N/A N/A N/A 2.837±0.00 N/A 3.187±0.00 1.874±0.00 1.294±0.00 N/A N/A 2.140±0.00 N/A
ENST00000620592 N/A N/A N/A 0.856±0.00 1.577±0.00 1.629±0.00 1.787±0.00 N/A 4.363±0.00 0.994±0.00 0.712±0.00 2.528±0.99 1.163±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00007S CIL_00007S_0002 CGP 4:173524969-174284264
CIL_00007V CIL_00007V_0002 CGP 4:174236658-174333380

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000151 NAS ubiquitin ligase complex
GO:0005086 IEA:IBA ARF guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005634 IBA nucleus
GO:0006511 NAS ubiquitin-dependent protein catabolic process
GO:0030036 IBA actin cytoskeleton organization
GO:0030054 IBA cell junction
GO:0032012 IEA regulation of ARF protein signal transduction
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007477 fbxo8 F-box protein 8 protein_coding Danio_rerio
ENSMUSG00000038206 Fbxo8 F-box protein 8 protein_coding Mus_musculus

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