C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T, brachyury homolog (mouse)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164458 T 9606 - 6:166157656-166168700 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296946 T-001 166157656-166168619 protein_coding
  ENST00000366871 T-002 166157656-166168700 protein_coding
  ENST00000366876 T-003 166158415-166167877 protein_coding
  ENST00000461348 T-004 166164606-166168671 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalTestisENST00000296946ENST00000366876ENST00000461348
Transcript ID Adrenal Testis
ENST00000296946 N/A 0.031±0.00
ENST00000366876 0.035±0.00 0.057±0.00
ENST00000461348 N/A 0.170±0.13

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0000790 IDA nuclear chromatin
GO:0000978 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001085 ISS RNA polymerase II transcription factor binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001191 ISS RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0001570 IEA vasculogenesis
GO:0001756 IEA somitogenesis
GO:0001839 IEA neural plate morphogenesis
GO:0001843 IEA neural tube closure
GO:0003007 IDA heart morphogenesis
GO:0003257 IDA positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003677 IEA DNA binding
GO:0003700 NAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA:IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007165 NAS signal transduction
GO:0007341 IEA penetration of zona pellucida
GO:0007498 TAS mesoderm development
GO:0007509 IEA mesoderm migration involved in gastrulation
GO:0008284 IEA positive regulation of cell proliferation
GO:0008595 TAS anterior/posterior axis specification, embryo
GO:0009653 IEA anatomical structure morphogenesis
GO:0009952 IEA anterior/posterior pattern specification
GO:0014028 IEA notochord formation
GO:0022414 IEA reproductive process
GO:0023019 IEA signal transduction involved in regulation of gene expression
GO:0030509 IEA BMP signaling pathway
GO:0030903 IEA notochord development
GO:0036342 IEA post-anal tail morphogenesis
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048706 IEA embryonic skeletal system development
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060349 IEA bone morphogenesis
GO:0060395 IEA SMAD protein signal transduction
GO:0061371 IEA determination of heart left/right asymmetry
GO:0090009 NAS primitive streak formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039806 ntlb no tail b protein_coding Danio_rerio
ENSMUSG00000062327 T brachyury protein_coding Mus_musculus

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