C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: T, brachyury homolog (mouse)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000296946 T-001 ENSG00000164458 9606 - 6:166157656-166168619 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; TestisENST00000296946
Transcript ID Testis
ENST00000296946 0.031±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0000790 IDA nuclear chromatin
GO:0000978 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001085 ISS RNA polymerase II transcription factor binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001191 ISS RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0001570 IEA vasculogenesis
GO:0001756 IEA somitogenesis
GO:0001839 IEA neural plate morphogenesis
GO:0001843 IEA neural tube closure
GO:0003007 IDA heart morphogenesis
GO:0003257 IDA positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003700 NAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA:IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007165 NAS signal transduction
GO:0007341 IEA penetration of zona pellucida
GO:0007498 TAS mesoderm development
GO:0007509 IEA mesoderm migration involved in gastrulation
GO:0008284 IEA positive regulation of cell proliferation
GO:0008595 TAS anterior/posterior axis specification, embryo
GO:0009653 IEA anatomical structure morphogenesis
GO:0009952 IEA anterior/posterior pattern specification
GO:0014028 IEA notochord formation
GO:0022414 IEA reproductive process
GO:0023019 IEA signal transduction involved in regulation of gene expression
GO:0030509 IEA BMP signaling pathway
GO:0030903 IEA notochord development
GO:0036342 IEA post-anal tail morphogenesis
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048706 IEA embryonic skeletal system development
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060349 IEA bone morphogenesis
GO:0060395 IEA SMAD protein signal transduction
GO:0061371 IEA determination of heart left/right asymmetry
GO:0090009 NAS primitive streak formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000074667 T-001 protein_coding Mus_musculus 0 1386
ENSMUST00000177118 T-003 protein_coding Mus_musculus 0 728
ENSMUST00000136922 T-002 protein_coding Mus_musculus 0 529
ENSDART00000115394 tbx19-201 protein_coding Danio_rerio 0 385
ENSDART00000150167 tbx19-001 protein_coding Danio_rerio 0 385

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