C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: brachyury
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000062327 T 10090 + 17:8434423-8442496 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000074667 T-001 8434423-8442496 protein_coding
  ENSMUST00000136922 T-002 8434925-8436992 protein_coding
  ENSMUST00000177118 T-003 8435411-8441742 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000074667ENSMUST00000136922ENSMUST00000177118
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000074667 0.036±0.00 N/A 0.007±0.00 0.182±0.08 0.027±0.01 0.019±0.00 0.013±0.00 0.016±0.01 0.044±0.02 0.024±0.00 0.158±0.13 0.017±0.01 0.065±0.04
ENSMUST00000136922 N/A N/A N/A N/A N/A N/A N/A 0.024±0.00 0.092±0.03 N/A 0.091±0.01 0.023±0.01 N/A
ENSMUST00000177118 0.116±0.07 0.131±0.06 0.020±0.00 0.205±0.08 N/A 0.031±0.01 0.065±0.02 0.013±0.01 0.060±0.00 0.100±0.00 0.254±0.18 0.051±0.00 0.134±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IMP chromatin
GO:0000790 IEA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001191 IDA RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0001570 IMP vasculogenesis
GO:0001756 IMP somitogenesis
GO:0001839 IMP neural plate morphogenesis
GO:0001843 IMP neural tube closure
GO:0003007 IEA heart morphogenesis
GO:0003257 IMP positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007341 IMP penetration of zona pellucida
GO:0007498 IMP mesoderm development
GO:0007509 IMP mesoderm migration involved in gastrulation
GO:0008284 IMP positive regulation of cell proliferation
GO:0009653 IMP anatomical structure morphogenesis
GO:0009952 IMP anterior/posterior pattern specification
GO:0014028 IMP notochord formation
GO:0022414 IMP reproductive process
GO:0023019 IDA signal transduction involved in regulation of gene expression
GO:0030509 IDA BMP signaling pathway
GO:0030903 IMP notochord development
GO:0036342 IGI post-anal tail morphogenesis
GO:0043565 IDA sequence-specific DNA binding
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048706 IMP embryonic skeletal system development
GO:0055007 NAS cardiac muscle cell differentiation
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060349 IGI bone morphogenesis
GO:0060395 IDA SMAD protein signal transduction
GO:0061371 IMP determination of heart left/right asymmetry

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039806 ntlb no tail b protein_coding Danio_rerio
ENSG00000164458 T T, brachyury homolog (mouse) protein_coding Homo_sapiens

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