C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenylate cyclase 1 (brain)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164742 ADCY1 9606 + 7:45574140-45723116 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000297323 ADCY1-001 45574522-45723116 protein_coding
  ENST00000432715 ADCY1-002 45574140-45664672 protein_coding
  ENST00000468353 ADCY1-003 45684385-45686040 retained_intron
  ENST00000621543 ADCY1-201 45574885-45664671 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000297323ENST00000621543
Transcript ID Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000297323 1.832±0.00 0.480±0.00 1.215±0.00 1.130±0.00 1.063±0.00 N/A N/A 0.200±0.16 N/A
ENST00000621543 N/A N/A N/A N/A N/A 0.415±0.00 0.125±0.00 0.415±0.17 0.919±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008WT CIL_0008WT_0001 VISTA 7:45262733-45867007
CIL_00072L CIL_00072L_0002 CGP 7:45574140-45893668

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004016 IEA adenylate cyclase activity
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005886 IDA plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006171 IEA cAMP biosynthetic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007189 TAS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007268 TAS synaptic transmission
GO:0007409 IEA axonogenesis
GO:0007616 IEA long-term memory
GO:0007623 IEA circadian rhythm
GO:0008294 NAS calcium- and calmodulin-responsive adenylate cyclase activity
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0010226 IEA response to lithium ion
GO:0016021 IEA integral component of membrane
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0034199 TAS activation of protein kinase A activity
GO:0035556 IEA intracellular signal transduction
GO:0042493 IEA response to drug
GO:0042752 ISS regulation of circadian rhythm
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0071377 TAS cellular response to glucagon stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068890 adcy1a adenylate cyclase 1a protein_coding Danio_rerio
ENSDARG00000088634 adcy1b adenylate cyclase 1b protein_coding Danio_rerio
ENSMUSG00000020431 Adcy1 adenylate cyclase 1 protein_coding Mus_musculus

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