C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MICAL-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164877 MICALL2 9606 - 7:1428465-1459502 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000297508 MICALL2-001 1434366-1459502 protein_coding
  ENST00000413446 MICALL2-007 1434366-1450536 nonsense_mediated_decay
  ENST00000460198 MICALL2-013 1437536-1438465 retained_intron
  ENST00000467394 MICALL2-004 1434360-1441524 retained_intron
  ENST00000467783 MICALL2-016 1434359-1440022 retained_intron
  ENST00000470807 MICALL2-015 1434366-1437913 retained_intron
  ENST00000471899 MICALL2-012 1434366-1438962 processed_transcript
  ENST00000472100 MICALL2-002 1428619-1459365 retained_intron
  ENST00000479007 MICALL2-005 1434366-1439871 retained_intron
  ENST00000482839 MICALL2-009 1445071-1447952 retained_intron
  ENST00000487156 MICALL2-010 1438925-1440727 retained_intron
  ENST00000487187 MICALL2-011 1436743-1439158 retained_intron
  ENST00000490608 MICALL2-008 1446657-1448033 retained_intron
  ENST00000493998 MICALL2-014 1428465-1437611 retained_intron
  ENST00000496184 MICALL2-003 1428479-1439431 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000297508ENST00000413446ENST00000467394ENST00000467783ENST00000470807ENST00000471899ENST00000472100ENST00000479007ENST00000487156ENST00000496184
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000297508 2.064±0.00 7.095±0.00 N/A 2.001±0.00 2.408±0.89 1.506±0.00 1.051±0.00 2.568±0.00 0.669±0.00 1.721±1.26 0.213±0.11 5.038±1.89 3.062±0.98 2.988±1.09
ENST00000413446 N/A N/A 0.058±0.00 N/A N/A 1.209±0.00 0.069±0.00 N/A 0.081±0.00 N/A N/A 1.406±0.00 N/A N/A
ENST00000467394 N/A N/A N/A N/A N/A 0.772±0.00 N/A N/A N/A 0.148±0.00 N/A 3.284±1.46 N/A 1.785±0.00
ENST00000467783 N/A N/A 0.282±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000470807 N/A N/A N/A N/A N/A N/A N/A 4.172±0.00 N/A N/A N/A 23.468±0.00 2.980±0.00 5.338±0.00
ENST00000471899 N/A N/A N/A N/A N/A N/A 0.041±0.00 N/A 0.788±0.00 N/A 0.437±0.00 N/A N/A 4.275±0.00
ENST00000472100 0.366±0.00 3.264±0.00 0.049±0.00 1.756±0.00 0.329±0.00 1.372±0.00 N/A 0.565±0.00 0.183±0.02 1.278±0.00 N/A 1.614±1.04 N/A 0.982±0.00
ENST00000479007 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.661±0.00 N/A N/A
ENST00000487156 N/A N/A N/A N/A N/A N/A N/A N/A 0.694±0.00 N/A N/A N/A N/A N/A
ENST00000496184 N/A N/A 0.083±0.00 N/A N/A N/A N/A N/A N/A 2.244±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008V5 CIL_0008V5_0001 VISTA 7:925518-1526682
CIL_0008DL CIL_0008DL_0001 VISTA 7:928196-1529533
CIL_0002H6 CIL_0002H6_0002 CGP 7:1232907-1459502
CIL_0000ZP CIL_0000ZP_0001 CGP 7:1428465-1504367

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 ISS stress fiber
GO:0005515 IEA protein binding
GO:0005886 ISS plasma membrane
GO:0005911 ISS cell-cell junction
GO:0005923 ISS tight junction
GO:0008270 IEA zinc ion binding
GO:0017137 IEA Rab GTPase binding
GO:0030041 ISS actin filament polymerization
GO:0031005 IDA filamin binding
GO:0031175 ISS neuron projection development
GO:0031532 ISS actin cytoskeleton reorganization
GO:0032432 ISS actin filament bundle
GO:0032456 ISS endocytic recycling
GO:0034446 ISS substrate adhesion-dependent cell spreading
GO:0042805 IEA actinin binding
GO:0043005 ISS neuron projection
GO:0051015 ISS actin filament binding
GO:0055037 ISS recycling endosome
GO:0070830 ISS tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017834 micall2b mical-like 2b protein_coding Danio_rerio
ENSDARG00000052694 micall2a mical-like 2a protein_coding Danio_rerio
ENSMUSG00000036718 Micall2 MICAL-like 2 protein_coding Mus_musculus

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