C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dishevelled-binding antagonist of beta-catenin 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000395153 DACT1-002 ENSG00000165617 9606 + 14:58638056-58648321 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000395153
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000395153 0.925±0.00 3.940±0.00 0.369±0.00 1.061±0.39 1.685±0.17 3.494±0.00 0.780±0.00 1.247±0.00 0.185±0.00 11.994±0.00 0.521±0.00 5.733±6.01 4.021±1.00 7.077±0.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001K6 CIL_0001K6_0001 CGP 14:58427385-58648321
CIL_0007Q5 CIL_0007Q5_0001 VISTA 14:58571064-59171064
CIL_0001K5 CIL_0001K5_0001 CGP 14:58633967-59371405

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0005080 ISS protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0008013 IDA beta-catenin binding
GO:0016055 IEA Wnt signaling pathway
GO:0030054 IEA cell junction
GO:0030177 IDA positive regulation of Wnt signaling pathway
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0030877 IDA beta-catenin destruction complex
GO:0031647 IDA regulation of protein stability
GO:0035412 IMP regulation of catenin import into nucleus
GO:0035413 IMP positive regulation of catenin import into nucleus
GO:0045202 IEA synapse
GO:0045732 IDA positive regulation of protein catabolic process
GO:0046329 IDA negative regulation of JNK cascade
GO:0048619 ISS embryonic hindgut morphogenesis
GO:0051018 IDA protein kinase A binding
GO:0070097 ISS delta-catenin binding
GO:2000095 ISS regulation of Wnt signaling pathway, planar cell polarity pathway
GO:2000134 IDA negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000061273 Dact1-001 protein_coding Mus_musculus 0 1323
ENSMUST00000150639 Dact1-002 protein_coding Mus_musculus 0 693

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