C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peroxiredoxin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165672 PRDX3 9606 - 10:119167703-119178833 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298510 PRDX3-001 119167703-119178833 protein_coding
  ENST00000463322 PRDX3-002 119173745-119174772 processed_transcript
  ENST00000494433 PRDX3-003 119168069-119170988 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000298510ENST00000494433
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000298510 28.713±0.00 44.742±0.00 25.580±0.00 33.383±5.55 40.102±22.59 33.350±10.84 54.473±36.49 85.191±14.30 43.163±28.97 22.875±7.30 41.507±3.76 35.597±19.20 35.946±15.47 22.789±14.24
ENST00000494433 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.747±0.00 N/A 1.691±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004GQ CIL_0004GQ_0002 CGP 10:119140767-119178833
CIL_0005VT CIL_0005VT_0001 CGP 10:119167703-119459742

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001893 IEA maternal placenta development
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0005769 IDA early endosome
GO:0005829 IDA cytosol
GO:0006979 IMP response to oxidative stress
GO:0007005 IMP mitochondrion organization
GO:0008022 IPI protein C-terminus binding
GO:0008284 IDA positive regulation of cell proliferation
GO:0008379 IDA thioredoxin peroxidase activity
GO:0008385 IPI IkappaB kinase complex
GO:0008785 NAS alkyl hydroperoxide reductase activity
GO:0016209 IEA antioxidant activity
GO:0016491 IEA oxidoreductase activity
GO:0018171 IDA peptidyl-cysteine oxidation
GO:0019900 IPI kinase binding
GO:0019901 IPI protein kinase binding
GO:0030099 ISS myeloid cell differentiation
GO:0032496 ISS response to lipopolysaccharide
GO:0033673 IDA negative regulation of kinase activity
GO:0034599 IDA cellular response to oxidative stress
GO:0034614 IMP cellular response to reactive oxygen species
GO:0042542 IDA response to hydrogen peroxide
GO:0042744 IMP hydrogen peroxide catabolic process
GO:0042802 IEA identical protein binding
GO:0043027 IMP cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0051881 IMP regulation of mitochondrial membrane potential
GO:0051920 IEA peroxiredoxin activity
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032102 prdx3 peroxiredoxin 3 protein_coding Danio_rerio
ENSMUSG00000024997 Prdx3 peroxiredoxin 3 protein_coding Mus_musculus

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